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Review

Recent Advances in Microfluidics-Based Chromatography—A Mini Review

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State Key Laboratory of Chemical Engineering and School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China
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Department of Chemical and Process Engineering, University of Moratuwa, Moratuwa 10400, Sri Lanka
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Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology and School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China
*
Author to whom correspondence should be addressed.
Separations 2021, 8(1), 3; https://doi.org/10.3390/separations8010003
Received: 25 November 2020 / Revised: 23 December 2020 / Accepted: 28 December 2020 / Published: 31 December 2020
Microfluidics-based liquid chromatography is based on the miniaturization of the different types of liquid chromatography (LC) systems (e.g., affinity, adsorption, size exclusion, ion exchange) on a microchip to perform on-chip separation of different types of analytes. On-chip chromatography finds applications in genomics, proteomics, biomarker discovery, and environmental analysis. Microfluidics-based chromatography has good reproducibility and small sample consumption. However, the on-chip chromatography fabrication techniques are often more challenging to perform than conventional LC column preparation. Different research groups have attempted to develop different techniques to fabricate microfluidics-based LC systems. In this review, we will summarize the recent advances in microfluidics-based chromatography. View Full-Text
Keywords: microfluidics; chromatography; on-chip; LC system microfluidics; chromatography; on-chip; LC system
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MDPI and ACS Style

Bao, B.; Wang, Z.; Thushara, D.; Liyanage, A.; Gunawardena, S.; Yang, Z.; Zhao, S. Recent Advances in Microfluidics-Based Chromatography—A Mini Review. Separations 2021, 8, 3. https://doi.org/10.3390/separations8010003

AMA Style

Bao B, Wang Z, Thushara D, Liyanage A, Gunawardena S, Yang Z, Zhao S. Recent Advances in Microfluidics-Based Chromatography—A Mini Review. Separations. 2021; 8(1):3. https://doi.org/10.3390/separations8010003

Chicago/Turabian Style

Bao, Bo, Zhichao Wang, Dilantha Thushara, Achini Liyanage, Sanja Gunawardena, Zaiyong Yang, and Shuangliang Zhao. 2021. "Recent Advances in Microfluidics-Based Chromatography—A Mini Review" Separations 8, no. 1: 3. https://doi.org/10.3390/separations8010003

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