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Hunting Molecules in Complex Matrices with SPME Arrows: A Review

Restek Corporation, Bellefonte, PA 16823, USA
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Those authors contributed equally to this work.
Separations 2020, 7(1), 12; https://doi.org/10.3390/separations7010012
Received: 1 August 2019 / Revised: 24 October 2019 / Accepted: 28 November 2019 / Published: 15 February 2020
(This article belongs to the Special Issue Development of Alternative Green Sample Preparation Techniques)
Thirty years since the invention and public disclosure of solid phase microextraction (SPME), the technology continues evolving and inspiring several other green extraction technologies amenable for the collection of small molecules present in complex matrices. In this manuscript, we review the fundamental and operational aspects of a novel SPME geometry that can be used to “hunt” target molecules in complex matrices: the SPME Arrow. In addition, a series of applications in environmental, food, cannabis and forensic analysis are succinctly covered. Finally, special emphasis is placed on novel interfaces to analytical instrumentation, as well as recent developments in coating materials for the SPME Arrow. View Full-Text
Keywords: SPME; green chemistry; air sampling; complex matrices; mass spectrometry SPME; green chemistry; air sampling; complex matrices; mass spectrometry
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Herrington, J.S.; Gómez-Ríos, G.A.; Myers, C.; Stidsen, G.; Bell, D.S. Hunting Molecules in Complex Matrices with SPME Arrows: A Review. Separations 2020, 7, 12.

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