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Volume 156, 01
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Volume 156, 01
 
 
Swiss Archives of Neurology, Psychiatry and Psychotherapy is published by MDPI from Volume 176 Issue 1 (2026). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with the previous journal publisher.

Swiss Arch. Neurol. Psychiatry Psychother., Volume 156, Issue 2 (01 2005) – 13 articles

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Book Review
Simone Spuler, Arpad von Moers, Herausgeber: Muskelkrankheiten. Grundlagen, Diagnostik und Therapie
by EMH Swiss Medical Publishers Ltd.
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 100; https://doi.org/10.4414/sanp.2005.01585 - 1 Jan 2005
Viewed by 42
Abstract
In den letzten wenigen Jahren haben sowohl die Molekulargenetik wie die mikroskopische Pathologie ganz wesentlich unser Verständnis der Entstehungsmechanismen und die nosologische Gliederung von Muskelkrankheiten geprägt [...] Full article
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Book Review
Johannes M. Fox, Johannes Jörg, Herausgeber: Neurologische Pharmakotherapie
by EMH Swiss Medical Publishers Ltd.
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 100; https://doi.org/10.4414/sanp.2005.01584 - 1 Jan 2005
Viewed by 32
Abstract
Das vorliegende Buch widerspiegelt den Wandel der Neurologie in den vergangenen 20 Jahren vom diagnostisch geprägten Fach zu einer Disziplin, die heutzutage auch pharmako- therapeutisch den Patienten zu helfen weiss [...] Full article
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Book Review
Mathias Bähr, Herausgeber: Neuroprotection. Models, Mechanisms and Therapies
by EMH Swiss Medical Publishers Ltd.
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 99; https://doi.org/10.4414/sanp.2005.01583 - 1 Jan 2005
Viewed by 28
Abstract
In diesem sehr ansprechend zusammengestellten Buchband geben international ausgewiesene Neurodegenerationsforscher einen Einblick in das Gebiet zentralnervöser Neurodegeneration und Neuroprotektion. Verschiedenste Krankheitsgebiete werden abgehandelt, wie zum Beispiel der Schlaganfall [...] Full article
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Book Review
Charles Duyckaerts, Florence Pasquier: Démences (Traité de neurologie)
by EMH Swiss Medical Publishers Ltd.
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 99; https://doi.org/10.4414/sanp.2005.01582 - 1 Jan 2005
Viewed by 30
Abstract
Les éditeurs de cet ouvrage ont achevé une tâche herculéenne en rassemblant non moins de 80 auteurs pour rédiger 66 chapitres sur les différentes formes de démences [...] Full article
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Book Review
Hans-Christoph Diener, Werner Hacke, Michael Forsting: Schlaganfall
by EMH Swiss Medical Publishers Ltd.
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 99; https://doi.org/10.4414/sanp.2005.01581 - 1 Jan 2005
Viewed by 24
Abstract
Aufgrund der rasanten Entwicklung in Diagnostik und Therapie diverser neurologischer Krankheitsbilder haben sich die Autoren entschlossen [...] Full article
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Article
Neurologist-in-training
by Patrik Michel
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 94-98; https://doi.org/10.4414/sanp.2005.01580 - 1 Jan 2005
Viewed by 39
Abstract
The aim of this section is to prepare the neurologist-in-training for the FMH examination, to confront her or him with specific problems of everyday neurological practice and to give him or her updates on recent controversies in clinical neurology. Full article
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Article
Der Gutachter im Spannungsfeld der Parteien und der Wissenschaft
by Hans Rudolf Stöckli
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 87-93; https://doi.org/10.4414/sanp.2005.01576 - 1 Jan 2005
Viewed by 30
Abstract
The role of the medical expert fundamentally transforms the normal relationship based on trust between the doctor and the patient.The patient is degraded to the status of a person who is to be judged without any claim to medical advice and support, the [...] Read more.
The role of the medical expert fundamentally transforms the normal relationship based on trust between the doctor and the patient.The patient is degraded to the status of a person who is to be judged without any claim to medical advice and support, the doctor to the status of an objective advisor to administrators and the courts, robbed of his healing commission, which defines the very being of a doctor.This gives rise to an atmosphere of tension which can easily lead to various unhelpful reactions from both the patient and the doctor, which can make it extremely difficult to arrive at the correct conclusion: on the patient’s side this can be aggravation, simulation, the concealing or trivialisation of facts and on the doctor’s side unhelpful emotional reactions, conscious or subconscious rejection or identification with the patient. A further area of tension, which may equally adversely affect the role of a medical expert, can be found between specialists and insurers or other initiators.The conflict with science occurs especially in the area of whiplash injuries and increases the tensions with the legal system. The following problem areas are listed together with the appropriate recommendations. 1. Inform the patient immediately at the first meeting clearly and extensively about the task of a medical expert and about his obligation to absolute neutrality. 2. Begin with an unstructured case history, let the patient describe his symptoms, cares and fears in his own words, show interest in him, show empathy and in this way win his trust. Only then follows the 3. Structured case history (via questions). This serves the purposes of clarification and completing the case history. 4. If possible, dictate the case history in the presence of the patient, explain any specialist terminology (which actually does not belong in a case history), ask him if anything is unclear, allow the patient to spontaneously clarify his statements during the dictation. In this way you demonstrate openness and guarantee a correct personal case history. Allow yourself plenty of time for this! 5. Put yourself in the position of the patient. He has to tell his story of suffering, which may go back over many years, in one or two hours to a doctor whom he does not know. Just after leaving the surgery, or a couple of days later, most patients remember facts which they have forgotten to mention, but which seem to be important to them. Give the patient the opportunity from the very beginning to make such additions, whether they are so important or not (most of them are not) is secondary. It all contributes to the establishment of trust. Personally, I inform the patients at the end of the first meeting that over the next few days they should make a note of anything they have forgotten and send me the main points to add to the case history. During the second or final meeting you can discuss the additions once again. 6. Discussion: Discuss the final report with the patient in a form that is easy for him to understand. Take sufficient time for this! Explain to him in simple terms how you arrive at your conclusions, maybe read him the relevant passages of the conclusions and therefore you should always pay attention that your choice of words is easily comprehensible. 7. Avoid any form of secrecy, inform the patient of his right to see the report. This way you will avoid later complaints and the patient will understand your position, even if it goes against him. Full article
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Article
Der medizinische Gutachter und die Gefahr seiner eigenen Psychodynamik
by Raymond Battegay
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 84-86; https://doi.org/10.4414/sanp.2005.01573 - 1 Jan 2005
Viewed by 25
Abstract
The personality of a medical expert consists not only of conscious and controlled parts, but also of an unconscious part. Because of the psychodynamics of the expert even the best will to maintain an objective view toward the client concerned cannot remove the [...] Read more.
The personality of a medical expert consists not only of conscious and controlled parts, but also of an unconscious part. Because of the psychodynamics of the expert even the best will to maintain an objective view toward the client concerned cannot remove the danger of not maintaining an unbiased attitude. The causes of these possible failures are discussed. Full article
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Article
Zur Kontroverse über die Priorität der Entdeckung der spontanen und evozierten hirnelektrischen Aktivität
by Kazimierz Karbowski and R. Bilski
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 80-83; https://doi.org/10.4414/sanp.2005.01579 - 1 Jan 2005
Cited by 1 | Viewed by 31
Abstract
Adolf Beck, a 27-year-old Polish physiologist from Krakow, published a report in the “Centralblatt für Physiologie” in November 1890 about a spontaneous and evoked electrical activity in the brain of dogs and rabbits. He showed that the spontaneous cerebral potential oscillations were not [...] Read more.
Adolf Beck, a 27-year-old Polish physiologist from Krakow, published a report in the “Centralblatt für Physiologie” in November 1890 about a spontaneous and evoked electrical activity in the brain of dogs and rabbits. He showed that the spontaneous cerebral potential oscillations were not related to heart and breathing rhythms, and mentioned a blockage of this activity by afferent excitations. Beck also found the response in the contralateral occipital cortex after the excitation of the eye with flashes of magnesium light. Much more experimental detail contains Beck’s doctoral thesis published 1891 in Polish, under the leadership of the famous physiologist Prof. Napoleon Cybulski. The priority of this discovery has been claimed by some other authors, especially – unjustifiably – by Ernst Fleischl v. Marxov from Vienna. It was proven that it was Richard Caton from Liverpool who had mentioned the spontaneous electrical activity in the brain of monkeys and rabbits first, in 1875. As his works were published in English and not in German, which was at that time the most used language in physiology, they remained unknown to many other researchers for 16 years. Later, Beck together with Cybulski, described the exact localisation of cortical responses evoked by different peripheral sensory excitations and presented this work in 1895, at the 3rd International Physiology Congress in Berne. Mary Brazier (1904–1995) from Massachusetts Hospital in Boston, the prominent neurophysiologist and expert of history of neurophysiology, was profoundly impressed by the scientific work of Beck. She took the initiative to translate, 1973, his full doctoral thesis from Polish into English. In the foreword Mary Brazier, among other things, notes that “Beck’s thesis […] gives us more experimental detail (as required for a doctorate) than Catons’s three reports in medical journals”. Full article
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Article
Déficience mentale et polyhandicap: de nouveaux défis
by Claude-André Dessibourg
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 75-79; https://doi.org/10.4414/sanp.2005.01575 - 1 Jan 2005
Viewed by 30
Abstract
A great many improvements have occurred in recent years, including the fields of obstetrics, neonatology and paediatrics. Nonetheless, mental deficiency and polyhandicap remain as crucial problems for our society. Environmental factors, prematurity, multigemellar and late pregnancies, alcohol and drug addictions, poor standards of [...] Read more.
A great many improvements have occurred in recent years, including the fields of obstetrics, neonatology and paediatrics. Nonetheless, mental deficiency and polyhandicap remain as crucial problems for our society. Environmental factors, prematurity, multigemellar and late pregnancies, alcohol and drug addictions, poor standards of living in developing countries, epidemics such as aids, malaria and rubella still are, among others, major challenges. Against this background, neurology and psychiatry may have a difficult position. First to be mentioned is the lack of neuropaediatricians. On the other hand, one must acknowledge that many handicapped persons, until recently, have been denied any adequate psychiatric follow-up. Adult neurologists have not been trained to the clinical specificities of this population. Some specialised consultants do exist, but the detection of the patients within institutions or from their homes on an ambulatory basis may be questioned. Globally, the basic and continuous training of caregivers can raise discussions. Modern medicine is doing its best all around child birth and during early infancy. Later on, one can observe some demedicalisation, the handicapped person being essentially granted a psycho-paedagogic follow-up. Our observation is that of a too great gap between the institutions’ files and the medical ones. New connections should be sought for between these two specialised worlds that have a historical tendency to ignore each other. Neurosciences have stood out in the past decades with a great deal of original breakthrough on diagnostic and therapeutic levels. These novel techniques must be applied to handicapped persons that were investigated several years ago.This is the case for neuroradiology, pharmacology, genetic counselling, biotechnology, neuropacemakers, communication apparatus and so forth. In no way, the person bearing learning disabilities should be closed into a diagnostic box sticked to routine and defeatism. A way to go through some of these challenges is specific education of medical students, general practitioners, neurologists and psychiatrists themselves, as well as the medical and psycho-educative personnel’s. For example, one must admit that generally, little is teached about child psychology and educational measures to medical students and that psychologists often do not get enough information about neurological diseases and syndromes. Finally, a constant coping of the institutions to the new parameters of aging and greater diversities of these populations is a must. As a conclusion, the great leap forward of medicine in the last century, including for what concerns the complex field of handicap has, from now on, to reinforce itself and invent new strategies: a transversal collaboration on all levels is needed between hospitals and institutions,medical doctors and educational personnel, psychiatrists and school psychologists.The medical secret itself and the many idiomatic languages have often been excuses to stay in one’s own ivory tower. However, things can evolve in the very respect of the patients, their families and the law. This multidisciplinary partnership is a key to a new capillarity of knowledge and its practical applications. Full article
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Article
Indikationen für Gamma-Knife-Behandlungen
by Thomas Mindermann
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 66-74; https://doi.org/10.4414/sanp.2005.01578 - 1 Jan 2005
Viewed by 31
Abstract
The first radiosurgical tool ever to be developed and used clinically is the gamma knife.The gamma knife has been invented by the neurosurgeon Lars Leksell for the treatment of intracranial neurosurgical conditions. The prototype was first used in Stockholm in 1968. Today, the [...] Read more.
The first radiosurgical tool ever to be developed and used clinically is the gamma knife.The gamma knife has been invented by the neurosurgeon Lars Leksell for the treatment of intracranial neurosurgical conditions. The prototype was first used in Stockholm in 1968. Today, the gamma knife is used for the treatment of intracranial benign and malignant tumours, the treatment of cerebral vascular malformations and functional neurosurgery. Until now, more than 300 000 patients have been treated with the gamma knife worldwide. Over the last ten years, the use of gamma knife radiosurgery has grown exponentially. Because of its unparalleled precision, the great experience with more than 1200 publications, the minimal inconvenience to the patient and the excellent results especially in complicated and inoperable brain tumours, gamma knife treatment is the gold standard of radiosurgery today. In benign brain tumours, such as meningioma, acoustic neuroma or pituitary adenoma, long-term local tumour control is achieved in more than 90% following gamma knife treatment. In patients with skull base- and posterior fossa-meningioma, neurological function of cranial nerves may often be restored with gamma knife treatment, if the patient is referred in time. In impending neurological deficits as may occur in anterior clinoid process meningioma, a timely gamma knife treatment may prevent the impending optic nerve deficit altogether. In patients with acoustic neurinoma, gamma knife treatment allows for an effective tumour control without surgical risks, such as facial nerve palsy, postoperative infection, cerebrospinal fluid leak, etc. Therefore, gamma knife treatment is today the preferred treatment over surgery in patients with Samii Grade I–III acoustic neuromas. In patients with pituitary adenoma, normalisation of endocrine overproduction may be achieved besides local tumour control. In malignant brain tumours such as metastasis, local tumour control is achieved in more than 80%. Even so-called radioresistant tumours such as metastases of malignant melanomas or renal cell carcinomas respond with excellent local tumour control rates of more than 90% following gamma knife treatment. In patients with brain metastasis, gamma knife treatment is a noninvasive way to maintain a high Karnofsky performance score throughout the course of the disease even in the presence of multiple brain metastases. In our experience in Zurich, patients with cerebral metastasis who have been treated with the gamma knife do not die from their cerebral disease but from the systemic progression of the tumour. In cerebral vascular malformations, obliteration rates at two years following gamma knife treatment typically range from 66 to 80%. In functional neurosurgery,gamma knife treatment is now mostly used for the treatment of trigeminal neuralgia. Success rates are around 80% with a delay for pain relief of several months. Gamma knife treatment is also used as a noninvasive way to achieve thalamotomy in patients with movement disorders.Another means of radiosurgery is the treatment with a linear accelerator. Often such treatments are performed without a stereotactic head frame, the various machines and software may differ considerably from one another and so may the treatment protocols and the experience of the team. Because of all those factors, reproducability and comparability of clinical results following linear accelerator treatments remain somewhat questionable. Full article
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Article
Troubles de la marche chez la personne âgée: aspects physiologiques et sémiologiques
by Christian Wider, F. Vingerhoets and J. Bogousslavsky
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 58-65; https://doi.org/10.4414/sanp.2005.01577 - 1 Jan 2005
Cited by 3 | Viewed by 42
Abstract
Human beings have the unique ability to walk in a bipedal manner, which, like language, makes them differ so much from even highly evolved animals. From a neurological point of view, the importance of gait analysis increased very much during the nineteenth century, [...] Read more.
Human beings have the unique ability to walk in a bipedal manner, which, like language, makes them differ so much from even highly evolved animals. From a neurological point of view, the importance of gait analysis increased very much during the nineteenth century, through eminent clinicians like Romberg, Bruns or Parkinson. It became clear that certain structures were essential in the complex sequence of events that permitted bipedal walking, the localisation of which was deduced from abnormal gait patterns in patients with particular neurological lesions.The importance of the frontal lobes was first underlined by Bruns in 1892 who described “frontal ataxia”. In the last century, further progress was made in the understanding of gait and gait disorders’ mechanisms with the use of technical means like electromyography, stroboscopic video, accelerometers, gyroscopes and computers. Gait disorders is a major problem in our oldgrowing population, being responsible for significant morbidity and even mortality, mainly through falls and bone fractures. It has been reported that more than 20% of old people fall each year. This article mentions some of the epidemiological data regarding this issue, underlining its public health relevance.The gait cycle is detailed, along with the main centres that are known to be involved in its processing, in animal experience and in the human being. The main gait disorders’ patterns are reviewed from a clinical point of view, beginning with “lower level” – often seen in patients with peripheral nervous system disease like polyneuropathy and characterised by an increased base of support, irregular steps and a positive Romberg’s sign. In the so-called “middle level” gait disorders, cervical myelopathy due to degenerative spondylosis is the most frequent and often overlooked cause, leading to slowly progressive spastic paraparesis, with lower motor neuron signs in the superior limbs, sensory abnormalities and sometimes urinary incontinence. Parkinsonian gait pattern is frequently encountered, with its small and shuffling steps, its stooped posture and the associated parkinsonism in the form of rest tremor, bradykinesia and rigidity. Many “higher level” gait disorders can mimic parkinsonian gait, for example in the first stage of normal-pressure hydrocephalus or in any lesion leading to a frontal gait disorder.This gait pattern often leaves superior limb movements quite unaffected – best exemplified by arm swing, and clinical examination frequently displays associated signs like dementia or urinary incontinence. Other “higher level” gait disorders include dysequilibrium – both frontal and subcortical, gait ignition failure, cautious gait and psychogenic gait disorders that are briefly discussed. The article ends with some practical information on how to deal with a patient presenting with gait disorders. Full article
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Article
Psychogenic nonepileptic seizures: diagnosis, aetiology, treatment and prognosis
by Markus Reuber
Swiss Arch. Neurol. Psychiatry Psychother. 2005, 156(2), 47-57; https://doi.org/10.4414/sanp.2005.01574 - 1 Jan 2005
Cited by 12 | Viewed by 58
Abstract
Psychogenic nonepileptic seizures (PNES) are episodes of altered movement, sensation or experience resembling epileptic seizures, but associated with pathopsychological processes and not with ictal electrical discharges in the brain. The prevalence of psychogenic nonepileptic seizures is equivalent to about 4% of that of [...] Read more.
Psychogenic nonepileptic seizures (PNES) are episodes of altered movement, sensation or experience resembling epileptic seizures, but associated with pathopsychological processes and not with ictal electrical discharges in the brain. The prevalence of psychogenic nonepileptic seizures is equivalent to about 4% of that of epilepsy. The early recognition of psychogenic nonepileptic seizures is important if delays in the treatment of underlying or associated psychopathology and iatrogenic harm due to inappropriate treatment of seizures with antiepileptic drugs are to be avoided. The most helpful pointers to a diagnosis of psychogenic nonepileptic seizures rather than epileptic events are perhaps seizures which occur in stressful situations (for instance seizures in front of a doctor), seizures of long duration (especially if they cause recurrent admissions to hospital), prolonged atonic seizures and closed eyes during tonic-cloniclike seizures. If the diagnosis of psychogenic nonepileptic seizures is suspected or the diagnosis of epilepsy is in doubt, the recording of a typical event with video-EEG should be considered. Seizure provocation techniques can be helpful in making a firm diagnosis in patients with infrequent seizures in whom no spontaneous event could be recorded with video-EEG monitoring. There is no single pathway to psychogenic nonepileptic seizures.A range of predisposing, precipitating or perpetuating factors can be identified. Childhood trauma (especially sexual abuse), stressful life events, a dysfunctional home and social environment, psychiatric comorbidity, personality pathology, epilepsy, learning disability and other “organic” brain disorders and abnormalities can all play an aetiological role. Different factors may interact with each other. Precipitating factors may allow patients to accept that there is a link between their emotions or thoughts and seizures. This can help clinicians to engage them in a therapeutic relationship. Perpetuating factors are often the main focus of treatment. Ongoing abuse, unresolvable dilemmas, poor coping strategies and communication, psychiatric comorbidity, low IQ and social status as well as financial and social illness gain commonly perpetuate psychogenic nonepileptic seizures. In view of the diversity of possible aetiological factors, treatment has to be tailored to individual patients. It should, however, share some common elements: the non-confrontational, sympathetic communication of the diagnosis and an offer of psychological treatment or case management for more intractable patients.There is no information about which form of psychological treatment is best at present. In the wider field of the psychological treatment of medically unexplained symptoms the evidence is strongest for variants of cognitive behavioural therapy, but psychoanalytical approaches have also been used. Medication has a limited (and usually purely supportive) role. Antidepressants can be used to modify emotional dysregulation and low-dose neuroleptics can be useful in some patients with distressing dissociative symptoms. At present, social and seizure outcome are poor. Over two thirds of patients continue to have seizures 12 years after manifestation and over half receive social benefits.The fact that many patients with psychogenic nonepileptic seizures continue to be treated with antiepileptic drugs by nonepilepsy specialists after a clear diagnosis of psychogenic nonepileptic seizures has been made suggests that specialist follow-up should be offered more widely to facilitate regular critical review and (if appropriate) retention of the diagnosis. It is hoped that earlier identification, improved communication of the diagnosis and the offer of appropriate psychological treatment to more patients will improve the outcome in the future. Full article
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