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GERMS is published by MDPI from Volume 25 Issue 4 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with the former publisher Infection Science Forum S.R.L..

GERMS, Volume 2, Issue 3 (09 2012) – 7 articles

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Communication
Rabies in Romania—Editorial Comment
by Oana Streinu-Cercel
GERMS 2012, 2(3), 122; https://doi.org/10.11599/germs.2012.1023 - 1 Sep 2012
Viewed by 18
Abstract
Rabies is an important health issue worldwide due to its high mortality and its possibly insidious outline determined by the relatively long incubation period, of three to eight weeks [...] Full article
106 KB  
Communication
Talactoferrin
by Hilary Denis Solomons
GERMS 2012, 2(3), 121; https://doi.org/10.11599/germs.2012.1022 - 1 Sep 2012
Cited by 4 | Viewed by 14
Abstract
Lactoferrin is a natural globular protein with a molecular atomic mass of 80 kD [...] Full article
245 KB  
Review
Recent Advances in the Diagnosis of Mycobacterium tuberculosis
by Philip Ifesinachi Anochie, Edwina C Onyeneke, Angelina C Ogu, Anthony C Onyeozirila, Srikanth Aluru, Nneka Onyejepu, Jian Zhang, Lauretta Efere, Mariam A Adetunji and Juan Gabriel Bueno Sánchez
GERMS 2012, 2(3), 110-120; https://doi.org/10.11599/germs.2012.1021 - 1 Sep 2012
Cited by 14 | Viewed by 11
Abstract
Molecular technologies offer the greatest potential for laboratories in resource-rich countries because they have the highest sensitivity and specificity. Continued use of new technologies will be crucial in elucidating the true epidemiology and pathogenesis of a disease, including the less well studied diseases. [...] Read more.
Molecular technologies offer the greatest potential for laboratories in resource-rich countries because they have the highest sensitivity and specificity. Continued use of new technologies will be crucial in elucidating the true epidemiology and pathogenesis of a disease, including the less well studied diseases. Continued development of affordable, sensitive, and specific diagnostic tools will be required for use in resource-poor settings, where the incidence of disease is highest. Full article
266 KB  
Review
Milk-Borne Infections: An Analysis of Their Potential Effect on the Milk Industry
by Revathi Dhanashekar, Sindhura Akkinepalli and Arvind Nellutla
GERMS 2012, 2(3), 101-109; https://doi.org/10.11599/germs.2012.1020 - 1 Sep 2012
Cited by 96 | Viewed by 17
Abstract
In developed countries such as the United States of America, foodborne illnesses account for 48 million infections per year. Developing countries such as India face greater simultaneous challenges particularly since incorrect processing or storage of dairy products can represent a transmission hazard for [...] Read more.
In developed countries such as the United States of America, foodborne illnesses account for 48 million infections per year. Developing countries such as India face greater simultaneous challenges particularly since incorrect processing or storage of dairy products can represent a transmission hazard for a large number of pathogens and can be responsible for outbreaks of brucellosis, listeriosis, tuberculosis, etc. It is important to recognize the types of germs which can be transmitted through insufficient thermal preparation of milk or milk products or through post-pasteurization contamination, in order to successfully avoid transmission of milk-borne infections. Full article
361 KB  
Article
Epidemiological Management of Rabies in Romania
by Hagit Najar and Anca Streinu-Cercel
GERMS 2012, 2(3), 95-100; https://doi.org/10.11599/germs.2012.1019 - 1 Sep 2012
Cited by 8 | Viewed by 23
Abstract
Introduction: Transmission of rabies to humans occurs rarely in Europe but in the absence of vaccination, it almost invariably leads to a fatal disease. In 2007, Romania implemented a program for rabies eradication in foxes. Methods: We performed a descriptive study evaluating the [...] Read more.
Introduction: Transmission of rabies to humans occurs rarely in Europe but in the absence of vaccination, it almost invariably leads to a fatal disease. In 2007, Romania implemented a program for rabies eradication in foxes. Methods: We performed a descriptive study evaluating the trend of rabies disease in Romania, both in animals and in humans, between 2008-2012. Results: In the past years, a large number of adults have presented to the Antirabic Center of the National Institute for Infectious Diseases “Prof.Dr. Matei Balş”, Bucharest, Romania. The major bite-inflicting animals were cats and dogs, particularly stray dogs (more than two thirds of the cases). Most cases of animal rabies were recorded in 2008 (1089 cases), with a subsequent decline in the following years: 516 in 2009, 469 in 2010, and 195 in 2011. Six cases of human rabies have been reported in Romania from 2008 to 2012, two of which were located in the Bacău district. Four of the cases occurred in females, and two in males; half were children and half adults. The animals inflicting the bites were domestic cats and stray dogs in half of the cases. Discussion: Domestic animals, particularly cats, appear to be a major cause of rabies transmission to humans. Therefore, vaccination after cat bites should be taken into account. There is stringent need for specific measures to increase the awareness regarding the problem. People should be educated that cats in rural areas or in the vicinity of forests pose the same level of risk as dogs or wild animals. Conclusions: There is need for a new strategy regarding the prevention of animal rabies and its transmission to humans. Proper surveillance systems and continuous monitoring for the disease in wildlife and cities is of utmost importance and should be continued, together with the programs for vaccination of stray dogs and foxes in order to eliminate rabies infection. Full article
147 KB  
Article
The Winding Road to Developing a Malaria Vaccine: Study Hypothesis
by Hilary Denis Solomons, Chris Gerhardus Joubert, Bonnie Beichter and Zelda Haefele
GERMS 2012, 2(3), 91-94; https://doi.org/10.11599/germs.2012.1018 - 1 Sep 2012
Cited by 1 | Viewed by 16
Abstract
In Africa, a child dies every 30 seconds from malaria, a vector-borne parasitic disease caused by Plasmodium spp, with higher mortality and severe forms of disease more frequently associated with Plasmodium falciparum infection. By looking at the natural resistance to malaria conferred by [...] Read more.
In Africa, a child dies every 30 seconds from malaria, a vector-borne parasitic disease caused by Plasmodium spp, with higher mortality and severe forms of disease more frequently associated with Plasmodium falciparum infection. By looking at the natural resistance to malaria conferred by sickle cell trait, we hypothesize that a malaria therapeutical vaccine targeting the erythrocyte stage of the parasite through erythrocyte sickling could reduce parasite density and control the progression and severity of disease, thus decreasing the morbidity and mortality associated with severe forms of malaria. Full article
155 KB  
Editorial
Nanoparticles
by Adrian Streinu-Cercel
GERMS 2012, 2(3), 90; https://doi.org/10.11599/germs.2012.1017 - 1 Sep 2012
Cited by 2 | Viewed by 15
Abstract
With the increasing number of treatment options for the human immunodeficiency virus (HIV) infection, we find ourselves more and more preoccupied with the route of administration of antiretrovirals and apparently, the future may yet hold some surprises [...] Full article
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