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Review

Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering

1
Centre de Recherche en Organogenèse Expérimentale de l’Université Laval/LOEX, Centre de Recherche du CHU de Québec-Université Laval, Axe Médecine Régénératrice, Québec City, QC G1J 1Z4, Canada
2
Department of Surgery, Faculty of Medicine, Université Laval, Québec City, QC G1V 0A6, Canada
*
Author to whom correspondence should be addressed.
Academic Editor: Tullio Genova
Processes 2021, 9(3), 513; https://doi.org/10.3390/pr9030513
Received: 15 February 2021 / Revised: 3 March 2021 / Accepted: 8 March 2021 / Published: 12 March 2021
(This article belongs to the Special Issue Biomaterials and Tissue Engineering)
Tissue engineering is one of the most promising scientific breakthroughs of the late 20th century. Its objective is to produce in vitro tissues or organs to repair and replace damaged ones using various techniques, biomaterials, and cells. Tissue engineering emerged to substitute the use of native autologous tissues, whose quantities are sometimes insufficient to correct the most severe pathologies. Indeed, the patient’s health status, regulations, or fibrotic scars at the site of the initial biopsy limit their availability, especially to treat recurrence. This new technology relies on the use of biomaterials to create scaffolds on which the patient’s cells can be seeded. This review focuses on the reconstruction, by tissue engineering, of two types of tissue with tubular structures: vascular and urological grafts. The emphasis is on self-assembly methods which allow the production of tissue/organ substitute without the use of exogenous material, with the patient’s cells producing their own scaffold. These continuously improved techniques, which allow rapid graft integration without immune rejection in the treatment of severely burned patients, give hope that similar results will be observed in the vascular and urological fields. View Full-Text
Keywords: tissue engineering; biomaterials; self-assembly; blood vessel; ureter; urethra tissue engineering; biomaterials; self-assembly; blood vessel; ureter; urethra
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MDPI and ACS Style

Caneparo, C.; Chabaud, S.; Bolduc, S. Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering. Processes 2021, 9, 513. https://doi.org/10.3390/pr9030513

AMA Style

Caneparo C, Chabaud S, Bolduc S. Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering. Processes. 2021; 9(3):513. https://doi.org/10.3390/pr9030513

Chicago/Turabian Style

Caneparo, Christophe, Stéphane Chabaud, and Stéphane Bolduc. 2021. "Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering" Processes 9, no. 3: 513. https://doi.org/10.3390/pr9030513

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