Sustainable Green Procedure for Extraction of Hesperidin from Selected Croatian Mandarin Peels
AbstractThe peels of Citrus reticulata Blanco mandarin cultivars of different Croatian varieties (Zorica rana, Chahara, Okitsu, Kuno) were extracted using 15 different choline chloride-based deep eutectic solvents (DESs) at 50 °C for 30 min and with 20% water addition. The extracts were analyzed by high performance liquid chromatography with diode array detection (HPLC-DAD) to determine the most suitable DES for the extraction of hesperidin in the samples. The screening results indicated that choline chloride: acetamide (1:2) provided the most efficient hesperidin extraction (112.14 mg/g of plant), while choline chloride:citric acid (1:1) solvent showed the lowest hesperidin yield (1.44 mg/g of plant). The Box–Behnken design was employed to optimize extraction parameters for each variety of mandarin peel, including extraction time, temperature and water content on hesperidin extraction. The results indicated that hesperidin content in mandarin peels was completely variety-dependent. Being a novel and efficient green media for hesperidin extraction, deep eutectic solvents could also serve as promising solvent systems for the production of extracts rich in bioactive compounds. View Full-Text
Share & Cite This Article
Jokić, S.; Šafranko, S.; Jakovljević, M.; Cikoš, A.-M.; Kajić, N.; Kolarević, F.; Babić, J.; Molnar, M. Sustainable Green Procedure for Extraction of Hesperidin from Selected Croatian Mandarin Peels. Processes 2019, 7, 469.
Jokić S, Šafranko S, Jakovljević M, Cikoš A-M, Kajić N, Kolarević F, Babić J, Molnar M. Sustainable Green Procedure for Extraction of Hesperidin from Selected Croatian Mandarin Peels. Processes. 2019; 7(7):469.Chicago/Turabian Style
Jokić, Stela; Šafranko, Silvija; Jakovljević, Martina; Cikoš, Ana-Marija; Kajić, Nikolina; Kolarević, Filip; Babić, Jurislav; Molnar, Maja. 2019. "Sustainable Green Procedure for Extraction of Hesperidin from Selected Croatian Mandarin Peels." Processes 7, no. 7: 469.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.