Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population

Bagkaki, Alena; Parthenakis, Fragiskos; Chlouverakis, Gregory; Anastasakis, Aris; Papagiannis, Ioannis; Galanakis, Emmanouil; Germanakis, Ioannis

doi:10.3390/children11060732

Open AccessArticle

Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population

by

Alena Bagkaki

¹

,

Fragiskos Parthenakis

¹,

Gregory Chlouverakis

¹,

Aris Anastasakis

²,

Ioannis Papagiannis

²,

Emmanouil Galanakis

¹

and

Ioannis Germanakis

^1,*

¹

School of Medicine, University of Crete, 71 003 Heraklion, Greece

²

Onassis Cardiac Surgery Center, Syggrou Av. 356, 176 74 Athens, Greece

^*

Author to whom correspondence should be addressed.

Children 2024, 11(6), 732; https://doi.org/10.3390/children11060732

Submission received: 14 May 2024 / Revised: 12 June 2024 / Accepted: 14 June 2024 / Published: 15 June 2024

(This article belongs to the Section Pediatric Cardiology)

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Abstract

Background. Our knowledge regarding the epidemiology of pediatric cardiomyopathy is based on large national population studies reporting an annual incidence of 1 case per 100,000 children, with a higher incidence observed in infancy and among selected populations. The aim here is to document the epidemiology of pediatric cardiomyopathy in a Mediterranean population. Methods. Children younger than 18 years of age living on the Mediterranean island of Crete, Greece, who have been evaluated since the establishment of tertiary pediatric cardiology services (2002–2022) were included in this retrospective study. Results. A total of 40 children were included, corresponding to an average annual incidence of pediatric cardiomyopathy of 1.59 cases (95% CI: 1.4–2.3) and a prevalence of 26 cases per 100,000 children. In decreasing order of frequency, most cases corresponded to dilated (50%), followed by hypertrophic (42.5%), arrhythmogenic (5%), and restrictive (2.5%) cardiomyopathy. An etiology was identified in 40%, including a genetic diagnosis in 22.5%. Conclusions. The incidence of pediatric cardiomyopathy in the Mediterranean island of Crete is higher compared with that reported previously for other Caucasian populations. Further study is needed to investigate the exact prevalence and specific genetic factors associated with the epidemiology of pediatric cardiomyopathy in Mediterranean populations.

Keywords: cardiomyopathy; childhood; pediatric cardiomyopathy; epidemiology; Crete; Mediterranean

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MDPI and ACS Style

Bagkaki, A.; Parthenakis, F.; Chlouverakis, G.; Anastasakis, A.; Papagiannis, I.; Galanakis, E.; Germanakis, I. Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population. Children 2024, 11, 732. https://doi.org/10.3390/children11060732

AMA Style

Bagkaki A, Parthenakis F, Chlouverakis G, Anastasakis A, Papagiannis I, Galanakis E, Germanakis I. Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population. Children. 2024; 11(6):732. https://doi.org/10.3390/children11060732

Chicago/Turabian Style

Bagkaki, Alena, Fragiskos Parthenakis, Gregory Chlouverakis, Aris Anastasakis, Ioannis Papagiannis, Emmanouil Galanakis, and Ioannis Germanakis. 2024. "Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population" Children 11, no. 6: 732. https://doi.org/10.3390/children11060732

APA Style

Bagkaki, A., Parthenakis, F., Chlouverakis, G., Anastasakis, A., Papagiannis, I., Galanakis, E., & Germanakis, I. (2024). Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population. Children, 11(6), 732. https://doi.org/10.3390/children11060732

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Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population

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