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Article

Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin

1
Department of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, Gunduliceva 5, 10000 Zagreb, Croatia
2
Department of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland
3
Community Health Center Zagreb—Center, Runjaninova 4, 10000 Zagreb, Croatia
*
Author to whom correspondence should be addressed.
Academic Editor: Vijay Kumar Thakur
Biomedicines 2021, 9(11), 1616; https://doi.org/10.3390/biomedicines9111616
Received: 28 September 2021 / Revised: 28 October 2021 / Accepted: 2 November 2021 / Published: 4 November 2021
(This article belongs to the Special Issue New Techniques and Materials for Biomedical Applications)
The purpose of this in vitro study was to investigate whether different types of experimental and commercial restorative dental materials can protect dentin against acid-induced softening. Experimental composites were prepared with a photocurable mixture of methacrylates and two types of bioactive glass (45S5 and a customized low-Na F-containing formulation). Human dentin samples were prepared from mid-coronal tooth slices and immersed in lactic acid solution (pH = 4.0) at 5 mm from set specimens of restorative material. After 4, 8, 12, 16, 20, 24, 28, and 32 days, surface microhardness of dentin samples and pH of the immersion solution were measured, followed by replenishing of the immersion medium. Microstructural analysis was performed using scanning electron microscopy. The protective effect of restorative materials was determined as dentin microhardness remaining statistically similar to initial values for a certain number of acid additions. Scanning electron microscopy showed a gradual widening of dentinal tubules and proved less discriminatory than microhardness measurements. To produce a protective effect on dentin, 20 wt% of low-Na F-containing bioactive glass was needed, whereas 10 wt% of bioactive glass 45S5 was sufficient to protect dentin against acid-induced demineralization. The anti-demineralizing protective effect of experimental and commercial restoratives on dentin was of shorter duration than measured for enamel in a previous study using the same experimental approach. View Full-Text
Keywords: experimental resin composites; remineralizing dental materials; bioactive glass; glass ionomer; alkasite; giomer experimental resin composites; remineralizing dental materials; bioactive glass; glass ionomer; alkasite; giomer
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MDPI and ACS Style

Par, M.; Gubler, A.; Attin, T.; Tarle, Z.; Tarle, A.; Tauböck, T.T. Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin. Biomedicines 2021, 9, 1616. https://doi.org/10.3390/biomedicines9111616

AMA Style

Par M, Gubler A, Attin T, Tarle Z, Tarle A, Tauböck TT. Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin. Biomedicines. 2021; 9(11):1616. https://doi.org/10.3390/biomedicines9111616

Chicago/Turabian Style

Par, Matej, Andrea Gubler, Thomas Attin, Zrinka Tarle, Andro Tarle, and Tobias T. Tauböck. 2021. "Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin" Biomedicines 9, no. 11: 1616. https://doi.org/10.3390/biomedicines9111616

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