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Open AccessCommunication

Possible Uses of Plants of the Genus Asphodelus in Oral Medicine

1
Department of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, 71122 Foggia, Italy
2
Department of Biomedical, Surgical, and Dental Science, University of Milan, 20122 Milan, Italy
3
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80121 Naples, Italy
*
Author to whom correspondence should be addressed.
Biomedicines 2019, 7(3), 67; https://doi.org/10.3390/biomedicines7030067
Received: 19 August 2019 / Accepted: 29 August 2019 / Published: 2 September 2019
(This article belongs to the Section Natural Compounds in Biomedicine)
Among the many plants used in traditional medicine we have the plants of the genus Asphodelus, which are present in the Mediterranean area in North Africa and South East Asia, and have been used by indigenous peoples until recently for various pathologies, including: Psoriasis, alopecia areata, acne, burns, nephrolithiasis, toothache, and local inflammation. The scientific literature over the last five years has investigated the various effects of the metabolites extracted from plants of the genus Asphodelus, paying attention to the diuretic, antihypertensive, antimicrobial, anti-inflammatory, and antioxidant effects, and it also has begun to investigate the antitumor properties on tumor cell lines. Studies have been identified through bibliographic research on electronic databases. A total of 574 records were identified on the PubMed, Scopus, Web of Science, and EBSCO databases. After having proceeded to the screening of the articles with the application of the eligibility criteria (all the articles pertaining to the issue Asphodelus), we arrived at a number of 163 articles, and then after the elimination of overlaps, to 82 articles. There are 11 articles which investigate the possible uses of plants of the genus Asphodelus in oral medicine. In oral medicine, the possible uses investigated by the scientific literature are for the treatment of neoplastic (melanoma and oral cancer), viral (herpetic viruses), and microbial diseases (candida, bacteriosis, leishmaniasis), and in the affection of the skin. View Full-Text
Keywords: Asphodelus microcarpus; Asphodelus tenuifolius; Asphodelus aestivus; oral medicine; medical plants; ethnomedicine; skin diseases Asphodelus microcarpus; Asphodelus tenuifolius; Asphodelus aestivus; oral medicine; medical plants; ethnomedicine; skin diseases
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Dioguardi, M.; Campanella, P.; Cocco, A.; Arena, C.; Malagnino, G.; Sovereto, D.; Aiuto, R.; Laino, L.; Laneve, E.; Dioguardi, A.; Zhurakivska, K.; Lo Muzio, L. Possible Uses of Plants of the Genus Asphodelus in Oral Medicine. Biomedicines 2019, 7, 67.

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