Next Article in Journal
Electrochemical Study of Enzymatic Glucose Sensors Biocatalyst: Thermal Degradation after Long-Term Storage
Previous Article in Journal
Fluorescence and Naked-Eye Detection of Pb2+ in Drinking Water Using a Low-Cost Ionophore Based Sensing Scheme
Previous Article in Special Issue
Advancements and Potential Applications of Microfluidic Approaches—A Review
Open AccessReview

Label-Free Biosensors Based onto Monolithically Integrated onto Silicon Optical Transducers

Immunoassay/Immunosensors Lab, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15310 Athens, Greece
*
Author to whom correspondence should be addressed.
Chemosensors 2018, 6(4), 52; https://doi.org/10.3390/chemosensors6040052
Received: 13 September 2018 / Revised: 2 November 2018 / Accepted: 6 November 2018 / Published: 12 November 2018
(This article belongs to the Special Issue Label-Free Biosensors and Chemical Sensors)
The article reviews the current status of label-free integrated optical biosensors focusing on the evolution over the years of their analytical performance. At first, a short introduction to the evanescent wave optics is provided followed by detailed description of the main categories of label-free optical biosensors, including sensors based on surface plasmon resonance (SPR), grating couplers, photonic crystals, ring resonators, and interferometric transducers. For each type of biosensor, the detection principle is first provided followed by description of the different transducer configurations so far developed and their performance as biosensors. Finally, a short discussion about the current limitations and future perspectives of integrated label-free optical biosensors is provided. View Full-Text
Keywords: integrated optical sensors; monolithic integration; broad-band interferometers; label-free; multiplexed detection; on-site determinations integrated optical sensors; monolithic integration; broad-band interferometers; label-free; multiplexed detection; on-site determinations
Show Figures

Figure 1

MDPI and ACS Style

Angelopoulou, M.; Kakabakos, S.; Petrou, P. Label-Free Biosensors Based onto Monolithically Integrated onto Silicon Optical Transducers. Chemosensors 2018, 6, 52.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop