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Volume 13
Issue 4
10.3390/chemosensors13040139
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Article

Silica Optical Fibers Connected via a Micro MIP-Core Waveguide to Build Optical-Chemical Sensors

by
Rosalba Pitruzzella
1,†,
Chiara Marzano
1,†,
Francesco Arcadio
1,
Filipa Sequeira
2,
Alessandra Cutaia
3,
Catarina Cardoso Novo
2,
Ricardo Oliveira
2,
Maria Pesavento
3,
Luigi Zeni
1,
Rogerio Nunes Nogueira
2,*,
Nunzio Cennamo
1,* and
Giancarla Alberti
3,*
1
Department of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy
2
Instituto de Telecomunicações, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal
3
Department of Chemistry, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Chemosensors 2025, 13(4), 139; https://doi.org/10.3390/chemosensors13040139
Submission received: 28 February 2025 / Revised: 4 April 2025 / Accepted: 8 April 2025 / Published: 10 April 2025
(This article belongs to the Special Issue The Recent Progress and Applications of Optical Chemical Sensors)
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Abstract

Molecularly imprinted polymers (MIPs) can be combined with optical fibers (OFs) to create various sensor configurations, yielding low-cost and highly sensitive extrinsic and intrinsic sensors. In this work, an MIP-based extrinsic optical fiber sensor is obtained by two silica OFs connected via an optical waveguide using an MIP as a core of micrometer size (micro OF-MIP-OF sensor). The proposed sensing approach can be used only with MIP receptors and implements an intensity-based sensor configuration. MIPs present several advantages over bio-receptors and can be exploited to realize novel sensing methods. The MIP used in this work is specifically designed for 2-furaldehyde (2-FAL) detection, and the experimental results demonstrate that the micro-probe performs well in terms of sensitivity and selectivity, with capabilities applicable to several application fields. In particular, a nanomolar detection range, from 1.5 nM to 150 nM, has been achieved. Moreover, the results are comparable to or better than those of other previously proposed MIP optical fiber sensors for 2-FAL, which employ more complex sensing principles or fabrication steps.
Keywords: molecularly imprinted polymers (MIP); optical fiber sensors; optical chemical sensors; 2-furaldehyde (2-FAL); intensity-based configuration; extrinsic optical fiber sensors molecularly imprinted polymers (MIP); optical fiber sensors; optical chemical sensors; 2-furaldehyde (2-FAL); intensity-based configuration; extrinsic optical fiber sensors

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MDPI and ACS Style

Pitruzzella, R.; Marzano, C.; Arcadio, F.; Sequeira, F.; Cutaia, A.; Cardoso Novo, C.; Oliveira, R.; Pesavento, M.; Zeni, L.; Nogueira, R.N.; et al. Silica Optical Fibers Connected via a Micro MIP-Core Waveguide to Build Optical-Chemical Sensors. Chemosensors 2025, 13, 139. https://doi.org/10.3390/chemosensors13040139

AMA Style

Pitruzzella R, Marzano C, Arcadio F, Sequeira F, Cutaia A, Cardoso Novo C, Oliveira R, Pesavento M, Zeni L, Nogueira RN, et al. Silica Optical Fibers Connected via a Micro MIP-Core Waveguide to Build Optical-Chemical Sensors. Chemosensors. 2025; 13(4):139. https://doi.org/10.3390/chemosensors13040139

Chicago/Turabian Style

Pitruzzella, Rosalba, Chiara Marzano, Francesco Arcadio, Filipa Sequeira, Alessandra Cutaia, Catarina Cardoso Novo, Ricardo Oliveira, Maria Pesavento, Luigi Zeni, Rogerio Nunes Nogueira, and et al. 2025. "Silica Optical Fibers Connected via a Micro MIP-Core Waveguide to Build Optical-Chemical Sensors" Chemosensors 13, no. 4: 139. https://doi.org/10.3390/chemosensors13040139

APA Style

Pitruzzella, R., Marzano, C., Arcadio, F., Sequeira, F., Cutaia, A., Cardoso Novo, C., Oliveira, R., Pesavento, M., Zeni, L., Nogueira, R. N., Cennamo, N., & Alberti, G. (2025). Silica Optical Fibers Connected via a Micro MIP-Core Waveguide to Build Optical-Chemical Sensors. Chemosensors, 13(4), 139. https://doi.org/10.3390/chemosensors13040139

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