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Open AccessArticle

Formaldehyde Detection by a Combination of Formaldehyde Dehydrogenase and Chitosan on a Sensor Based on an Organic Field-Effect Transistor

1
Research Center for Organic Electronics (ROEL), Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata 992-8510, Japan
2
Biotechnology Group, Tokyo Metropolitan Industrial Technology Research Institute, 2-4-10 Aomi, Koto-ku, Tokyo 135-0064, Japan
3
Innovative Flex Course for Frontier Organic Material Systems (iFront), Graduate School of Science and Engineering, Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata 992-8510, Japan
4
Graduate School of Organic Materials Science, Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata 992-8510, Japan
5
Material Application Laboratory, Japan Research Center, Huawei Technologies Japan K.K., 3-1 Kinko-cho, Kanagawa-ku, Yokohama, Kanagawa 221-0056, Japan
*
Authors to whom correspondence should be addressed.
Technologies 2019, 7(3), 48; https://doi.org/10.3390/technologies7030048
Received: 9 June 2019 / Revised: 30 June 2019 / Accepted: 1 July 2019 / Published: 4 July 2019
(This article belongs to the Special Issue Smart Systems (SmaSys2018))
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Abstract

Formaldehyde is utilized for the preservation of materials due to its strong bactericidal effects. As formaldehyde is also a harmful substance that causes health hazards, the quantitative monitoring of formaldehyde in natural and living environments is desirable. For the rapid and easy detection of formaldehyde, in this study we applied an organic field-effect transistor (OFET)-based sensor that can function as a potentiometric device for electrochemical measurements. A polyion-complex gel of formaldehyde dehydrogenase (FDH) and chitosan (CT) was constructed on a gold electrode. When the FDH/CT gel-coated electrode was connected to an OFET device it could detect formaldehyde in an aqueous solution, in which the amino groups of chitosan would protonate during the enzymatic reaction. The limit of detection was calculated to be 3.1 µM (93 ppb), demonstrating the applicability of the film-type OFET sensor to environmental monitoring. View Full-Text
Keywords: chitosan; formaldehyde dehydrogenase (FDH); formaldehyde detection; organic field-effect transistor (OFET); polyion-complex gel chitosan; formaldehyde dehydrogenase (FDH); formaldehyde detection; organic field-effect transistor (OFET); polyion-complex gel
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Tsuchiya, K.; Furusawa, H.; Nomura, A.; Matsui, H.; Nihei, M.; Tokito, S. Formaldehyde Detection by a Combination of Formaldehyde Dehydrogenase and Chitosan on a Sensor Based on an Organic Field-Effect Transistor. Technologies 2019, 7, 48.

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