Implementation of Smart Infusion Pumps: A Scoping Review and Case Study Discussion of the Evidence of the Role of the Pharmacist
Abstract
:1. Introduction
2. Method
3. Results
3.1. Procurement
3.2. Implementation Strategy
3.2.1. Risk Assessment
3.2.2. Device Distribution
3.2.3. Drug Library Creation
3.2.4. Training
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Cousins, D.; National Patient Safety Agency (Great Britain), Patient Safety Observatory. Safety in Doses: Medication Safety Incidents in the NHS: The Fourth Report from the Patient Safety Observatory; National Patient Safety Agency: London, UK, 2007.
- Blandford, A.; Dykes, P.C.; Franklin, B.D.; Furniss, D.; Galal-Edeen, G.; Schnock, K.O.; Bates, D.W. Intravenous Infusion Administration: A Comparative Study of Practices and Errors between the United States and England and Their Implications for Patient Safety. Drug Saf. 2019, 42, 1157–1165. [Google Scholar] [CrossRef] [Green Version]
- Schnock, K.O.; Dykes, P.C.; Albert, J.; Ariosto, D.; Call, R.; Cameron, C.; Carroll, D.L.; Drucker, A.G.; Fang, L.; Garcia-Palm, C.A.; et al. The frequency of intravenous medication administration errors related to smart infusion pumps: A multihospital observational study. BMJ Qual. Saf. 2017, 26, 131–140. [Google Scholar] [CrossRef] [PubMed]
- Blandford, A.; Furniss, D.; Lyons, I.; Chumbley, G.; Iacovides, I.; Wei, L.; Cox, A.; Mayer, A.; Schnock, K.; Bates, D.W.; et al. Exploring the Current Landscape of Intravenous Infusion Practices and Errors (ECLIPSE): Protocol for a mixed-methods observational study. BMJ Open 2016, 6, e009777. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Ohashi, K.; Dalleur, O.; Dykes, P.C.; Bates, D.W. Benefits and Risks of Using Smart Pumps to Reduce Medication Error Rates: A Systematic Review. Drug Saf. 2014, 37, 1011–1020. [Google Scholar] [CrossRef] [PubMed]
- Trbovich, P.L.; Cafazzo, J.A.; Easty, A.C. Implementation and Optimization of Smart Infusion Systems: Are we Reaping the Safety Benefits? J. Health Qual. 2013, 35, 33–40. [Google Scholar] [CrossRef]
- Iacovides, I.; Blandford, A.; Cox, A.; Franklin, B.D.; Lee, P.; Vincent, C.J. Infusion device standardisation and dose error reduction software. Br. J. Nurs. 2014, 23, S16–S24. [Google Scholar] [CrossRef]
- WHO. The Third WHO Global Patient Safety Challenge: Medication without Harm. Available online: http://www.who.int/patientsafety/medication-safety/en/ (accessed on 2 October 2020).
- Ibarra-Pérez, R.; Puértolas-Balint, F.; Lozano-Cruz, E.; Zamora-Gómez, S.E.; Castro-Pastrana, L.I. Intravenous Administration Errors Intercepted by Smart Infusion Technology in an Adult Intensive Care Unit. J. Patient Saf. 2017. publish ahead of print. [Google Scholar] [CrossRef]
- Manrique-Rodríguez, S.; Sánchez-Galindo, A.; Fernández-Llamazares, C.M.; Lopez-Herce, J.; García-López, I.; Carrillo-Álvarez, Á.; Sanjuro-Sáez, M. Developing a drug library for smart pumps in a pediatric intensive care unit. Artif. Intell. Med. 2012, 54, 155–161. [Google Scholar] [CrossRef]
- Manrique-Rodríguez, S.; Sánchez-Galindo, A.C.; López-Herce, J.; Calleja-Hernández, M.Á.; Martínez-Martínez, F.; Iglesias-Peinado, I.; Carrillo-Álvarez, Á.; Sáez, M.S.; Fernández-Llamazares, C.M. Impact of implementing smart infusion pumps in a pediatric intensive care unit. Am. J. Health Pharm. 2013, 70, 1897–1906. [Google Scholar] [CrossRef]
- Dimech, A.; Le Page, A.; Gruber, P.; Wigmore, T. Making drug delivery in the ICU safer: The implementation of advanced computerised intravenous infusion pumps. Crit. Care 2012, 16, P501. [Google Scholar] [CrossRef] [Green Version]
- Jani, Y.H.; Chumbley, G.M.; Furniss, D.; Blandford, A.; Franklin, B. The Potential Role of Smart Infusion Devices in Preventing or Contributing to Medication Administration Errors: A Descriptive Study of 2 Data Sets. J. Patient Saf. 2020. publish ahead of print. [Google Scholar] [CrossRef] [PubMed]
- Borthwick, M.; Keeling, S.; Keeling, P.; Scales, K.; Waldmann, C. Towards Standardisation of Drug Infusion Concentrations in UK Critical Care Units. J. Intensive Care Soc. 2009, 10, 197–200. [Google Scholar] [CrossRef]
- NHS Injectable Medicines Guide Group. NHS Injectable Medicines Guide. Available online: www.medusa.wales.nhs.uk (accessed on 14 December 2020).
- Gerhart, D.; O’Shea, K.; Muller, S. Advancing Medication Infusion Safety Through the Clinical Integration of Technology. Hosp. Pract. 2013, 41, 7–14. [Google Scholar] [CrossRef] [PubMed]
- Walroth, T.A.; Smallwood, S.; Arthur, K.; Vance, B.; Washington, A.; Staublin, T.; Haslar, T.; Reddan, J.G.; Fuller, J. Development of a standardized, citywide process for managing smart-pump drug libraries. Am. J. Health Pharm. 2018, 75, 893–900. [Google Scholar] [CrossRef]
- Wetterneck, T.B.; Skibinski, K.A.; Roberts, T.L.; Kleppin, S.M.; Schroeder, M.E.; Enloe, M.; Rough, S.S.; Hundt, A.S.; Carayon, P. Using failure mode and effects analysis to plan implementation of smart i.v. pump technology. Am. J. Health Pharm. 2006, 63, 1528–1538. [Google Scholar] [CrossRef]
- NHS Digital. DCB0160: Clinical Risk Management: Its Application in the Deployment and Use of Health IT Systems. Available online: https://digital.nhs.uk/data-and-information/information-standards/information-standards-and-data-collections-including-extractions/publications-and-notifications/standards-and-collections/dcb0160-clinical-risk-management-its-application-in-the-deployment-and-use-of-health-it-systems (accessed on 2 October 2020).
- Larsen, G.Y.; Parker, H.B.; Cash, J.; O’Connell, M.; Grant, M.C. Standard Drug Concentrations and Smart-Pump Technology Reduce Continuous-Medication-Infusion Errors in Pediatric Patients. Pediatrics 2005, 116, e21–e25. [Google Scholar] [CrossRef] [Green Version]
- Manrique-Rodríguez, S.; Sánchez-Galindo, A.; Lopez-Herce, J.; Calleja-Hernández, M.Á.; Iglesias-Peinado, I.; Carrillo-Álvarez, Á.; Sáez, M.S.; Fernández-Llamazares, C.M. Risks in the Implementation and Use of Smart Pumps in A Pediatric Intensive Care Unit: Application of the Failure Mode and Effects Analysis. Int. J. Technol. Assess. Health Care 2014, 30, 210–217. [Google Scholar] [CrossRef]
- Howlett, M.; Curtin, M.; Doherty, D.; Gleeson, P.; Sheerin, M.; Breatnach, C. Paediatric Standardised Concentration Infusions—A National Solution. Arch. Dis. Child. 2016, 101, e2. [Google Scholar] [CrossRef]
- Butler, E.; Breatnach, C. Standard concentration infusions and “smart” pumps in PICU: The challenge of change. Arch. Dis. Child. 2013, 98, e1. [Google Scholar] [CrossRef]
- Manrique-Rodríguez, S.; Sánchez-Galindo, A.; Lopez-Herce, J.; Calleja-Hernández, M.Á.; Martinez-Martinez, F.; Iglesias-Peinado, I.; Carrillo-Álvarez, Á.; Sanjurjo-Saez, M.; Fernández-Llamazares, C.M. Implementing smart pump technology in a pediatric intensive care unit: A cost-effective approach. Int. J. Med. Inform. 2014, 83, 99–105. [Google Scholar] [CrossRef]
- Kennerly, J.; Jenkins, A.; Lewis, A.N.; Eckel, S.F. Implementing smart pumps for epidural infusions in an academic medical center. Am. J. Health Pharm. 2012, 69, 607–611. [Google Scholar] [CrossRef] [PubMed]
- Brown, T.D.; Michael, M.; Grady, D.S. Implementation of Smart Pump Technology With Home Infusion Providers: An Assessment of Clinician Workflow and Patient Satisfaction. J. Infus. Nurs. 2018, 41, 344–349. [Google Scholar] [CrossRef]
- Namshirin, P. Applying a Multidisciplinary Approach to the Selection, Evaluation, and Acquistion of Smart Infusion Pumps. J. Med. Biol. Eng. 2011, 31, 93. [Google Scholar] [CrossRef]
- ESCP International Workshop Patients: Infections and the Clinical Pharmacist—ProQuest. Available online: https://www.proquest.com/docview/1086480896/fulltextPDF/E12E8D5892B149C5PQ/1?accountid=50325 (accessed on 4 October 2020).
- Breland, B.D. Continuous quality improvement using intelligent infusion pump data analysis. Am. J. Health Pharm. 2010, 67, 1446–1455. [Google Scholar] [CrossRef] [PubMed]
- Furniss, D.; Franklin, B.D.; Blandford, A. The devil is in the detail: How a closed-loop documentation system for IV infusion administration contributes to and compromises patient safety. Health Inform. J. 2019. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- ResearchGate. Making Smart Pumps Smarter: Utilizing Electronic Medical Administration Record Information to Optimize Dose Error Reduction Software on Large Volume Infusion Devices. Available online: https://www.researchgate.net/publication/267915151_Making_Smart_Pumps_smarter_Utilizing_electronic_medical_administration_record_information_to_optimize_dose_error_reduction_software_on_large_volume_infusion_devices (accessed on 2 October 2020).
Author and Year of Publication | Objective | Intervention | Outcomes | Setting | Standardised Concentration Infusions Used? | Who Was Involved in the Development of the Drug Library? |
---|---|---|---|---|---|---|
Brown T.D. et al., 2018 [26] | Smart pump technology not available for home infusions | Creation of a drug library for home infusion providers | Successfully implemented a drug library for home infusions. | Hospital based and rural based home infusion providers | Not stated | Three clinical pharmacists at one site; two nurses and one pharmacist at another site |
Butler E. et al., 2013 [23] | Use standardised concentration infusions | Compile a drug library of standard concentrations drugs to be administered on paediatric intensive care unit | Standard concentration switch was successfully implemented. | Paediatric intensive care | Yes | Paediatric intensive care unit consultant and pharmacist. |
Chuk A.C. et al., 2012 [19] | Quality improvement (QI) project to administration of intravenous medicines | QI review of the pumps DERS data enabled further optimisation of the drug library | DERS limits within the drug library were able to be added or optimised based on medication use throughout the centre | Academic medical centre | Yes | Pharmacy and therapeutics drug library subcommittee (involves pharmacists, nurses, analysts and patient safety staff). |
Delage E. et al., 2012 [28] | Evaluate feasibility of including anti-infectives with useful limits and evaluate user satisfaction | Develop a drug library for anti-infective medicines | It is feasible to integrate anti-infectives with useful limits into the drug library if there is a standard concentration and administration times are standardised. | Anti-infectives only at a mother and child university hospital centre | Yes | Pharmacists and physicians |
Dimech A. et al., 2012 [12] | Implement smart pumps in the intensive care unit (ICU) to aid safer drug administration | Develop a drug library and implement smart pumps | Drug errors reduced; the design of the drug library was sensitive enough to ensure safe drug administration and was practical enough to enable consistent use of the system. | Intensive care unit | Not stated | ICU pharmacist and consultant intensivist. |
Gerhart et al., 2013 [16] | Describing implementation of intravenous clinical integration (IVCI) | Implementing intravenous clinical integration | A 27% reduction in nursing time achieved with the use of the integrated system when starting and documenting each new infusion. Numerous steps in the process of manually programming the pumps are eliminated with the IVCI process. | 10 outpatient health centres and 3 hospitals | No | Biomedical engineering, pharmacy and nursing |
Howlett M. et al., 2016 [22] | Standardising drug concentrations | Expansion of a drug library that was set-up with standardised concentration infusions in a paediatric hospital | Successful amendments and extension to the original drug library | Paediatrics hospital | Yes | Multidisciplinary with pharmacy input |
Kennerly J. et al., 2012 [25] | Describes the experience with implementation of smart infusion pumps for epidurals | Develop a drug library for all epidural infusions and update the order sets within the computerised prescriber order entry (CPOE) system | Limited data postimplementation as used keystroke recordings but need for education highlighted. Smart pumps do not ensure improved patient care. | Epidural infusions only at an 803-bed academic medical centre | Not stated | Clinical pharmacist, physicians and nurses |
Larsen G.Y. et al., 2005 [20] | Combining standard strength concentrations with smart pump technology reduced reported medication infusion errors | Adoption of standard drug concentrations, implementation of smart syringe pumps and medication label re-engineering | A 73% reduction in the number of reported errors associated with continuous medication infusions. Preparation errors that occurred in the pharmacy decreased from 0.66 to 0.16 per 1000 doses. The number of 10-fold errors in dosage decreased from 0.41 to 0.08 per 1000 doses. | 242-bed tertiary paediatric hospital | Yes | Nursing, pharmacy, clinical engineering, physicians (neonatologist, paediatric intensivist, cardiothoracic surgeon, and anaesthesiologist) and the safety manager for the hospital. |
Manrique-Rodriguez S. et al., 2014 [21] | Identify risk points in different stages of the smart infusion pumps implementation process | Failure modes and effects analysis carried out preimplementation and post implementation of smart pumps—to identify actions for improvement. | Appropriate risk assessments made it possible to ensure risks are managed during implementation. | Paediatric intensive care | Not stated | Two intensive care paediatricians, two clinical pharmacists and a nurse manager, with a pharmacist being responsible for the whole process |
Manrique-Rodriguez S. et al., 2014 [24] | Cost effectiveness of smart pump technology | Development and implementation of a drug library and analysis of reports of intercepted errors | Smart pump technology implementation is cost effective. An estimated EUR 172,279 were saved by prevented adverse effects. | Paediatric intensive care | Not stated | Two intensive care paediatricians, two clinical pharmacists and a nurse manager |
Manrique-Rodriguez S. et al., 2012 [10] | Develop a drug library to help prevent serious medication errors occurring during intravenous administration | Development of a drug library for IV drugs that were commonly used or classified as high-risk or that posed issues with administration | Compliance was 85%. In total, 94% of PICU nurses would recommend implementing this technology in other units. Several potential harmful infusion-related programming errors were prevented | 11-bed paediatric intensive care unit | Yes | Clinical pharmacist, PICU paediatrician and chief nurse for the unit |
Namshirin P. et al., 2011 [27] | Commentary/descriptive article | Selection of a suitable device—formalising human factors analysis in the purchasing protocol for medical devices | Team was successful in choosing an infusion pump with DERS that met the needs of all stakeholders | Ambulatory | Not stated | Anaesthesiology, nursing, pharmacy purchasing, biomedical engineering quality and patient safety and human factors experts |
Walroth T.A. et al., 2018 [17] | Reduce clinically insignificant alerts from smart infusion pumps | Development and implementation of an inter-professional consensus to review and optimise the drug library and dosing limits | Review of total number of alerts per smart pump revealed a 50% decrease in the median number of alerts per device over a 4-year period. | 6 health systems | Yes | Pharmacists and nurses from each of the 6 representative health systems and industrial engineers |
Wetterneck T.B. et al., 2006 [18] | Identify risks of implementation of smart pumps and evaluate IV pump technologies that could improve pump programming accuracy and decrease errors with IV medication | Failure mode and effects analysis (FMEA) was used to guide successful implementation | FMEA is a useful tool for implementation of smart pumps with DERS. Further refinements were required for paediatric concentrations | Hospital—a tertiary care, academic medical centre | Yes, for adults only | Anaesthesiology physicians, equipment, biomedical and industrial engineers, internal medicine, nursing, pharmacy, and quality improvement carried out FMEA. Drug library developed by pharmacists, nurses, an anaesthesia engineer and physicians. |
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Shah, N.; Jani, Y. Implementation of Smart Infusion Pumps: A Scoping Review and Case Study Discussion of the Evidence of the Role of the Pharmacist. Pharmacy 2020, 8, 239. https://doi.org/10.3390/pharmacy8040239
Shah N, Jani Y. Implementation of Smart Infusion Pumps: A Scoping Review and Case Study Discussion of the Evidence of the Role of the Pharmacist. Pharmacy. 2020; 8(4):239. https://doi.org/10.3390/pharmacy8040239
Chicago/Turabian StyleShah, Neha, and Yogini Jani. 2020. "Implementation of Smart Infusion Pumps: A Scoping Review and Case Study Discussion of the Evidence of the Role of the Pharmacist" Pharmacy 8, no. 4: 239. https://doi.org/10.3390/pharmacy8040239