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Plants 2017, 6(4), 48; https://doi.org/10.3390/plants6040048

An Investigation of the Antioxidant Capacity in Extracts from Moringa oleifera Plants Grown in Jamaica

1
Biotechnology Centre, University of the West Indies, Mona Kingston 8, Jamaica
2
Caribbean Institute for Health Research, University of the West Indies, Mona Kingston 8, Jamaica
3
Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS 39217, USA
4
Department of Pediatrics, Aflac Cancer and Blood Disorder Center, Children’s Healthcare of Atlanta and Emory University, Atlanta, GA 30322, USA
5
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
6
Biochemistry Section, Department of Basic Medical Sciences, University of the West Indies, Mona Kingston 8, Jamaica
*
Author to whom correspondence should be addressed.
Academic Editor: Milan S. Stankovic
Received: 18 September 2017 / Revised: 27 September 2017 / Accepted: 28 September 2017 / Published: 23 October 2017
(This article belongs to the Special Issue Medicinal Plants and Natural Product Research)
Full-Text   |   PDF [1000 KB, uploaded 23 October 2017]   |  

Abstract

Moringa oleifera trees grow well in Jamaica and their parts are popularly used locally for various purposes and ailments. Antioxidant activities in Moringa oleifera samples from different parts of the world have different ranges. This study was initiated to determine the antioxidant activity of Moringa oleifera grown in Jamaica. Dried and milled Moringa oleifera leaves were extracted with ethanol/water (4:1) followed by a series of liquid–liquid extractions. The antioxidant capacities of all fractions were tested using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. IC50 values (the amount of antioxidant needed to reduce 50% of DPPH) were then determined and values for the extracts ranged from 177 to 4458 μg/mL. Extracts prepared using polar solvents had significantly higher antioxidant capacities than others and may have clinical applications in any disease characterized by a chronic state of oxidative stress, such as sickle cell anemia. Further work will involve the assessment of these extracts in a sickle cell model of oxidative stress. View Full-Text
Keywords: Moringa oleifera; DPPH; antioxidant activity; oxidative stress; sickle cell anemia Moringa oleifera; DPPH; antioxidant activity; oxidative stress; sickle cell anemia
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Wright, R.J.; Lee, K.S.; Hyacinth, H.I.; Hibbert, J.M.; Reid, M.E.; Wheatley, A.O.; Asemota, H.N. An Investigation of the Antioxidant Capacity in Extracts from Moringa oleifera Plants Grown in Jamaica. Plants 2017, 6, 48.

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