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Article

LC-MS/MS Profiles and In Vitro Biological Activities of Extracts of an Endemic Species from Turkey: Stachys cretica ssp. anatolica

by 1,2,3,* and 4
1
Faculty of Chemistry and Technology, University of Split, Ruđera Boškovića 35, 21000 Split, Croatia
2
NAOS Institute of Life Science, 355, rue Pierre-Simon Laplace, 13290 Aix-en-Provence, France
3
Mediterranean Institute for Life Science, Meštrovićevo šetalište 45, 21000 Split, Croatia
4
Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar 03150, Turkey
*
Author to whom correspondence should be addressed.
Academic Editors: Simon Vlad Luca, Adriana Trifan and Gokhan Zengin
Plants 2021, 10(6), 1054; https://doi.org/10.3390/plants10061054
Received: 10 May 2021 / Revised: 18 May 2021 / Accepted: 19 May 2021 / Published: 25 May 2021
(This article belongs to the Special Issue Polyphenols in Plants)
Background: Genus Stachys is one of the largest of the Lamiaceae family, having around 300 different plant species inhabiting areas with temperate and warm climates. The Stachys species in Turkey are represented with 81 taxa; 51 of them being endemic. Plants of the Stachys genus have been known for their biological activity and their use in ethnomedicine. Methods: The dominant components of S. cretica ssp. anatolica aqueous and methanol extracts were studied with the LC-MS/MS technique. Results: Chlorogenic acid, apigenin-7-glucoside and verbascoside present as the dominant polyphenols found in studied extracts. The prominent biological activity of the studied S. cretica ssp. anatolica methanol and aqueous extracts showed strong antioxidant activity and inhibition of enzymes tyrosinase and α-amylase, involved in skin disorders and diabetes mellitus type II. Conclusions: This study has proven that the aqueous and methanol extracts of S. cretica ssp. anatolica have prominent antioxidant activity, due to a high abundance of polyphenols. The strong antioxidant properties of S. cretica ssp. anatolica extracts show promising application for the pharmaceutical, food, and cosmetics industries. View Full-Text
Keywords: Stachys; antioxidant; phenolics; flavonoids; LC-MS/MS; tyrosinase; α-amylase Stachys; antioxidant; phenolics; flavonoids; LC-MS/MS; tyrosinase; α-amylase
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MDPI and ACS Style

Carev, I.; Sarikurkcu, C. LC-MS/MS Profiles and In Vitro Biological Activities of Extracts of an Endemic Species from Turkey: Stachys cretica ssp. anatolica. Plants 2021, 10, 1054. https://doi.org/10.3390/plants10061054

AMA Style

Carev I, Sarikurkcu C. LC-MS/MS Profiles and In Vitro Biological Activities of Extracts of an Endemic Species from Turkey: Stachys cretica ssp. anatolica. Plants. 2021; 10(6):1054. https://doi.org/10.3390/plants10061054

Chicago/Turabian Style

Carev, Ivana, and Cengiz Sarikurkcu. 2021. "LC-MS/MS Profiles and In Vitro Biological Activities of Extracts of an Endemic Species from Turkey: Stachys cretica ssp. anatolica" Plants 10, no. 6: 1054. https://doi.org/10.3390/plants10061054

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