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Review

Phytochemical, Pharmacological, and Biotechnological Study of Ageratina pichinchensis: A Native Species of Mexico

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Departamento de Biotecnología, Universidad Autónoma Metropolitana-Iztapalapa, Av. Ferrocarril de San Rafael Atlixco 186, Col. Leyes de Reforma 1a. Sección, Alcaldía Iztapalapa, Ciudad de México C.P. 09310, Mexico
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Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa, Cuernavaca C.P. 62209, Mexico
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Departamento de Madera, Celulosa y Papel, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Km. 15.5, Carretera Guadalajara-Nogales, Col. Las Agujas, Zapopan C.P. 45020, Mexico
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Authors to whom correspondence should be addressed.
Academic Editors: Laura Grațiela Vicaș and Mariana Eugenia Mureșan
Plants 2021, 10(10), 2225; https://doi.org/10.3390/plants10102225
Received: 27 August 2021 / Revised: 14 October 2021 / Accepted: 14 October 2021 / Published: 19 October 2021
(This article belongs to the Special Issue Medicinal Plant Extracts)
Ageratina pichinchensis (Asteraceae) has been used for a long time in traditional Mexican medicine for treating different skin conditions and injuries. This review aimed to provide an up-to-date view regarding the traditional uses, chemical composition, and pharmacological properties (in vitro, in vivo, and clinical trials) that have been achieved using crude extracts, fractions, or pure compounds. Moreover, for a critical evaluation of the published literature, key databases (Pubmed, Science Direct, and SciFinder, among others) were systematically searched using keywords to retrieve relevant publications on this plant. Studies that reported on crude extracts, fractions, or isolated pure compounds of A. pichinchensis have found a varied range of biological effects, including antibacterial, curative, antiulcer, antifungal, and anti-inflammatory activities. Phytochemical analyses of different parts of A. pichinchensis revealed 47 compounds belonging to chromenes, furans, glycosylated flavonoids, terpenoids, and essential oils. Furthermore, biotechnological studies of A. pichinchensis such as callus and cell suspension cultures have provided information for future research perspectives to improve the production of valuable bioactive compounds. View Full-Text
Keywords: botanical description; ethnomedicinal uses; standardized extracts; bioactive compounds; biotechnology botanical description; ethnomedicinal uses; standardized extracts; bioactive compounds; biotechnology
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MDPI and ACS Style

Sánchez-Ramos, M.; Marquina-Bahena, S.; Alvarez, L.; Román-Guerrero, A.; Bernabé-Antonio, A.; Cruz-Sosa, F. Phytochemical, Pharmacological, and Biotechnological Study of Ageratina pichinchensis: A Native Species of Mexico. Plants 2021, 10, 2225. https://doi.org/10.3390/plants10102225

AMA Style

Sánchez-Ramos M, Marquina-Bahena S, Alvarez L, Román-Guerrero A, Bernabé-Antonio A, Cruz-Sosa F. Phytochemical, Pharmacological, and Biotechnological Study of Ageratina pichinchensis: A Native Species of Mexico. Plants. 2021; 10(10):2225. https://doi.org/10.3390/plants10102225

Chicago/Turabian Style

Sánchez-Ramos, Mariana, Silvia Marquina-Bahena, Laura Alvarez, Angélica Román-Guerrero, Antonio Bernabé-Antonio, and Francisco Cruz-Sosa. 2021. "Phytochemical, Pharmacological, and Biotechnological Study of Ageratina pichinchensis: A Native Species of Mexico" Plants 10, no. 10: 2225. https://doi.org/10.3390/plants10102225

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