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Regulation of Actin Dynamics in the C. elegans Somatic Gonad

Department of Biology, Northeastern University, Boston, MA 02115, USA
Author to whom correspondence should be addressed.
J. Dev. Biol. 2019, 7(1), 6;
Received: 17 February 2019 / Revised: 13 March 2019 / Accepted: 15 March 2019 / Published: 20 March 2019
(This article belongs to the Special Issue Caenorhabditis elegans - A Developmental Genetic Model System)
PDF [1038 KB, uploaded 20 March 2019]


The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus. Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized acto-myosin networks in each cell type. Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo. View Full-Text
Keywords: actin cytoskeleton; C. elegans; spermatheca; sheath; contractility actin cytoskeleton; C. elegans; spermatheca; sheath; contractility

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Kelley, C.A.; Cram, E.J. Regulation of Actin Dynamics in the C. elegans Somatic Gonad. J. Dev. Biol. 2019, 7, 6.

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