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Regulation of Actin Dynamics in the C. elegans Somatic Gonad

Department of Biology, Northeastern University, Boston, MA 02115, USA
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J. Dev. Biol. 2019, 7(1), 6; https://doi.org/10.3390/jdb7010006
Received: 17 February 2019 / Revised: 13 March 2019 / Accepted: 15 March 2019 / Published: 20 March 2019
(This article belongs to the Special Issue Caenorhabditis elegans - A Developmental Genetic Model System)
The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus. Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized acto-myosin networks in each cell type. Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo. View Full-Text
Keywords: actin cytoskeleton; C. elegans; spermatheca; sheath; contractility actin cytoskeleton; C. elegans; spermatheca; sheath; contractility
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Kelley, C.A.; Cram, E.J. Regulation of Actin Dynamics in the C. elegans Somatic Gonad. J. Dev. Biol. 2019, 7, 6.

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