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Mesothelium and Malignant Mesothelioma

Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
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J. Dev. Biol. 2019, 7(2), 7; https://doi.org/10.3390/jdb7020007
Received: 4 March 2019 / Revised: 2 April 2019 / Accepted: 5 April 2019 / Published: 8 April 2019
The mesothelium is an epithelial structure derived from the embryonic mesoderm. It plays an important role in the development of a number of different organs, including the heart, lungs, and intestines. In this publication, we discuss aspects of the development of the mesothelium, where mesothelial structures can be found, and review molecular and cellular characteristics associated with the mesothelium. Furthermore, we discuss the involvement of the mesothelium in a number of disease conditions, in particular in the pathogenesis of mesotheliomas with an emphasis on malignant pleural mesothelioma (MPM)—a primary cancer developing in the pleural cavity. View Full-Text
Keywords: mesothelium; development; malignant; mesothelioma; cancer mesothelium; development; malignant; mesothelioma; cancer
MDPI and ACS Style

Hiriart, E.; Deepe, R.; Wessels, A. Mesothelium and Malignant Mesothelioma. J. Dev. Biol. 2019, 7, 7.

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