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Journal of Developmental Biology, Volume 5, Issue 2

2017 June - 3 articles

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Articles (3)

  • Feature Paper
  • Review
  • Open Access
55 Citations
11,246 Views
15 Pages

Sonic Hedgehog Signaling and Development of the Dentition

  • Maisa Seppala,
  • Gareth J. Fraser,
  • Anahid A. Birjandi,
  • Guilherme M. Xavier and
  • Martyn T. Cobourne

Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates. Signal transduction is involved in early specification of the...

  • Review
  • Open Access
24 Citations
10,023 Views
17 Pages

A substantial amount of data has highlighted the crucial influence of Shh signalling on the generation of diverse classes of neurons and glial cells throughout the developing central nervous system. A critical step leading to this diversity is the es...

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J. Dev. Biol. - ISSN 2221-3759