Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Immunohistochemistry
2.3. Western Blotting
2.4. Statistical Analysis
3. Results
3.1. Chracteristics of PCOS in Our Model
3.2. Alterations of Insulin Receptor Signaling and Autophagy in the Liver
3.3. Alterations of Insulin Receptor Signaling and Autophagy in the Ovaries
3.4. Nitrative Stress in the Liver and in the Ovaries
3.5. Changes of Vitamin D Receptor Immunostaining in the Liver and the Ovaries
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Lajtai, K.; Nagy, C.T.; Tarszabó, R.; Benkő, R.; Hadjadj, L.; Sziva, R.E.; Gerszi, D.; Bányai, B.; Ferdinandy, P.; Nádasy, G.L.; et al. Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome. Biomolecules 2019, 9, 471. https://doi.org/10.3390/biom9090471
Lajtai K, Nagy CT, Tarszabó R, Benkő R, Hadjadj L, Sziva RE, Gerszi D, Bányai B, Ferdinandy P, Nádasy GL, et al. Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome. Biomolecules. 2019; 9(9):471. https://doi.org/10.3390/biom9090471
Chicago/Turabian StyleLajtai, Krisztina, Csilla Terézia Nagy, Róbert Tarszabó, Rita Benkő, Leila Hadjadj, Réka Eszter Sziva, Dóra Gerszi, Bálint Bányai, Péter Ferdinandy, György László Nádasy, and et al. 2019. "Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome" Biomolecules 9, no. 9: 471. https://doi.org/10.3390/biom9090471