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Bioactive Compounds: Natural Defense Against Cancer?

1
Pathology Division, School of Medicine, International Medical University, Bukit Jalil, Kuala Lumpur 50050, Malaysia
2
Product Development and Advisory Services, Malaysian Palm Oil Board, Kajang, Selangor 43000, Malaysia
3
Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Selangor 47500, Malaysia
*
Author to whom correspondence should be addressed.
Biomolecules 2019, 9(12), 758; https://doi.org/10.3390/biom9120758
Received: 15 October 2019 / Revised: 14 November 2019 / Accepted: 15 November 2019 / Published: 21 November 2019
(This article belongs to the Special Issue Biomolecules and Cancer Prevention)
Cancer is a devastating disease that has claimed many lives. Natural bioactive agents from plants are gaining wide attention for their anticancer activities. Several studies have found that natural plant-based bioactive compounds can enhance the efficacy of chemotherapy, and in some cases ameliorate some of the side-effects of drugs used as chemotherapeutic agents. In this paper, we have reviewed the literature on the anticancer effects of four plant-based bioactive compounds namely, curcumin, myricetin, geraniin and tocotrienols (T3) to provide an overview on some of the key findings that are related to this effect. The molecular mechanisms through which the active compounds may exert their anticancer properties in cell and animal-based studies also discussed. View Full-Text
Keywords: bioactive compounds; anticancer; curcumin; myricetin; geraniin; tocotrienols bioactive compounds; anticancer; curcumin; myricetin; geraniin; tocotrienols
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Subramaniam, S.; Selvaduray, K.R.; Radhakrishnan, A.K. Bioactive Compounds: Natural Defense Against Cancer? Biomolecules 2019, 9, 758.

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