Next Article in Journal
Microbial Fortification Improved Photosynthetic Efficiency and Secondary Metabolism in Lycopersicon esculentum Plants Under Cd Stress
Next Article in Special Issue
A Landauer Formula for Bioelectronic Applications
Previous Article in Journal
Highly Sensitive and Rapid Characterization of the Development of Synchronized Blood Stage Malaria Parasites Via Magneto-Optical Hemozoin Quantification
Previous Article in Special Issue
Mechanical Deformation and Electronic Structure of a Blue Copper Azurin in a Solid-State Junction
Open AccessArticle

Can One Define the Conductance of Amino Acids?

1
Departamento de Física Teórica de la Materia Condensada, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain
2
Condensed Matter Physics Center (IFIMAC), Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain
3
Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands
4
Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain
5
Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanociencia), Campus Universitario de Cantoblanco, E-28049 Madrid, Spain
*
Authors to whom correspondence should be addressed.
Biomolecules 2019, 9(10), 580; https://doi.org/10.3390/biom9100580
Received: 28 August 2019 / Revised: 16 September 2019 / Accepted: 26 September 2019 / Published: 7 October 2019
(This article belongs to the Special Issue Biomolecular Electronics)
We studied the electron-transport properties of ten different amino acids and one dimer (di-methionine) using the mechanically controlled break-junction (MCBJ) technique. For methionine and cysteine, additional measurements were performed with the scanning tunneling microscope break-junction (STM-BJ) technique. By means of a statistical clustering technique, we identified several conductance groups for each of the molecules considered. Ab initio calculations revealed that the observed broad conductance distribution stems from the possibility of various binding geometries which can be formed during stretching combined with a multitude of possible conformational changes. The results suggest that it would be helpful to explore different experimental techniques such as recognition tunneling and conditions to help identify the nature of amino-acid-based junctions even further, for example, with the goal to establish a firm platform for their unambiguous recognition by tunneling break-junction experiments. View Full-Text
Keywords: break junctions; DFT; NEGF; amino acids; electron transport; biomolecular electronics break junctions; DFT; NEGF; amino acids; electron transport; biomolecular electronics
Show Figures

Figure 1

MDPI and ACS Style

Zotti, L.A.; Bednarz, B.; Hurtado-Gallego, J.; Cabosart, D.; Rubio-Bollinger, G.; Agrait, N.; van der Zant, H.S. Can One Define the Conductance of Amino Acids? Biomolecules 2019, 9, 580.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop