Next Article in Journal
Application of Zebrafish Model in the Suppression of Drug-Induced Cardiac Hypertrophy by Traditional Indian Medicine Yogendra Ras
Previous Article in Journal
Expression Profile and Prognostic Significance of EPHB3 in Colorectal Cancer
Open AccessReview

The Pharmacological Activity of Camellia sinensis (L.) Kuntze on Metabolic and Endocrine Disorders: A Systematic Review

1
Department of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain
2
Department of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
Biomolecules 2020, 10(4), 603; https://doi.org/10.3390/biom10040603
Received: 26 March 2020 / Revised: 7 April 2020 / Accepted: 8 April 2020 / Published: 13 April 2020
Tea made from Camellia sinensis leaves is one of the most consumed beverages worldwide. This systematic review aims to update Camellia sinensis pharmacological activity on metabolic and endocrine disorders. Inclusion criteria were preclinical and clinical studies of tea extracts and isolated compounds on osteoporosis, hypertension, diabetes, metabolic syndrome, hypercholesterolemia, and obesity written in English between 2014 and 2019 and published in Pubmed, Science Direct, and Scopus. From a total of 1384 studies, 80 reports met inclusion criteria. Most papers were published in 2015 (29.3%) and 2017 (20.6%), conducted in China (28.75%), US (12.5%), and South Korea (10%) and carried out with extracts (67.5%, especially green tea) and isolated compounds (41.25%, especially epigallocatechin gallate). Most pharmacological studies were in vitro and in vivo studies focused on diabetes and obesity. Clinical trials, although they have demonstrated promising results, are very limited. Future research should be aimed at providing more clinical evidence on less studied pathologies such as osteoporosis, hypertension, and metabolic syndrome. Given the close relationship among all endocrine disorders, it would be of interest to find a standard dose of tea or their bioactive constituents that would be beneficial for all of them. View Full-Text
Keywords: Camellia sinensis; metabolic disorders; endocrine disorders; tea Camellia sinensis; metabolic disorders; endocrine disorders; tea
Show Figures

Figure 1

MDPI and ACS Style

Sánchez, M.; González-Burgos, E.; Iglesias, I.; Lozano, R.; Gómez-Serranillos, M.P. The Pharmacological Activity of Camellia sinensis (L.) Kuntze on Metabolic and Endocrine Disorders: A Systematic Review. Biomolecules 2020, 10, 603. https://doi.org/10.3390/biom10040603

AMA Style

Sánchez M, González-Burgos E, Iglesias I, Lozano R, Gómez-Serranillos MP. The Pharmacological Activity of Camellia sinensis (L.) Kuntze on Metabolic and Endocrine Disorders: A Systematic Review. Biomolecules. 2020; 10(4):603. https://doi.org/10.3390/biom10040603

Chicago/Turabian Style

Sánchez, Marta; González-Burgos, Elena; Iglesias, Irene; Lozano, Rafael; Gómez-Serranillos, M. P. 2020. "The Pharmacological Activity of Camellia sinensis (L.) Kuntze on Metabolic and Endocrine Disorders: A Systematic Review" Biomolecules 10, no. 4: 603. https://doi.org/10.3390/biom10040603

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop