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Open AccessEditorial

How A Novel Scientific Concept Was Coined the “Molten Globule State”

Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan
School of Science, Kitasato University, Sagamihara, Kanagawa 252-0373, Japan
Institute for Protein Research, Osaka University, Osaka 565-0871, Japan
Author to whom correspondence should be addressed.
Biomolecules 2020, 10(2), 269;
Received: 30 January 2020 / Accepted: 7 February 2020 / Published: 10 February 2020
As a tribute to Professor Oleg B. Ptitsyn, we organized an interview with Professor Akiyoshi Wada held in Tokyo in the middle of September 2019. Both Professor A. Wada and the late Professor O. B. Ptitsyn greatly contributed to the field of protein biophysics, and they played leading roles in establishing the concept of the “Molten Globule state” 35–40 years ago. This editorial is intended to recount, as accurately as possible, some episodes during the early days of protein research that led to the discovery of this state, and how this concept was coined the “Molten Globule state” and came to be widely accepted by biophysicists, biochemists, and molecular biologists.
Keywords: Molten Globule state; Akiyoshi Wada; Oleg B. Ptitsyn Molten Globule state; Akiyoshi Wada; Oleg B. Ptitsyn
MDPI and ACS Style

Kuroda, Y.; Endo, S.; Nakamura, H. How A Novel Scientific Concept Was Coined the “Molten Globule State”. Biomolecules 2020, 10, 269.

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