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Essential Oils of Lamiaceae Family Plants as Antifungals

Department of Medical Microbiology, Poznań University of Medical Sciences, Wieniawskiego 3, 61-712 Poznań, Poland
Biomolecules 2020, 10(1), 103; https://doi.org/10.3390/biom10010103 (registering DOI)
Received: 3 December 2019 / Revised: 3 January 2020 / Accepted: 6 January 2020 / Published: 7 January 2020
(This article belongs to the Special Issue Perspectives of Essential Oils)
The incidence of fungal infections has been steadily increasing in recent years. Systemic mycoses are characterized by the highest mortality. At the same time, the frequency of infections caused by drug-resistant strains and new pathogens e.g., Candida auris increases. An alternative to medicines may be essential oils, which can have a broad antimicrobial spectrum. Rich in the essential oils are plants from the Lamiaceae family. In this review are presented antifungal activities of essential oils from 72 Lamiaceae plants. More than half of these have good activity (minimum inhibitory concentrations (MICs) < 1000 µg/mL) against fungi. The best activity (MICs < 100) have essential oils from some species of the genera Clinopodium, Lavandula, Mentha, Thymbra, and Thymus. In some cases were observed significant discrepancies between different studies. In the review are also shown the most important compounds of described essential oils. To the chemical components most commonly found as the main ingredients include β-caryophyllene (41 plants), linalool (27 plants), limonene (26), β-pinene (25), 1,8-cineole (22), carvacrol (21), α-pinene (21), p-cymene (20), γ-terpinene (20), and thymol (20). View Full-Text
Keywords: Labiatae; fungi; Aspergillus; Cryptococcus; Penicillium; dermatophytes; β-caryophyllene; sesquiterpene; monoterpenes; minimal inhibitory concentration (MIC) Labiatae; fungi; Aspergillus; Cryptococcus; Penicillium; dermatophytes; β-caryophyllene; sesquiterpene; monoterpenes; minimal inhibitory concentration (MIC)
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Karpiński, T.M. Essential Oils of Lamiaceae Family Plants as Antifungals. Biomolecules 2020, 10, 103.

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