Natural Antioxidants from Acmella oleracea Extract as Dermatocosmetic Actives
Abstract
:1. Introduction
2. Materials and Methods
2.1. Plant Material
2.2. A. oleracea Extract
2.3. Evaluation of the Mineral Content of the Dried Plant
2.4. Evaluation of the Main Phytoconstituents of the Extract
2.5. Evaluation of the Antioxidant Activity of the Extract
2.6. The Methodology of Obtaining the Emulsion Based on the Extract of A. oleraceea
2.7. Characterization of Emulsion
2.7.1. Microbiological Control
2.7.2. Rheological Measurements
2.7.3. Analysis of Homogeneity of the Emulsion
2.7.4. In Vitro Evaluation of the Emulsion
3. Results
3.1. Determination of Minerals from the Initial Plant Sample
3.2. Vegetal Extract Characterized
3.3. Characterization the Obtained Emulsion
3.3.1. Microbiological Control
3.3.2. Analysis of Homogeneity of the Emulsion
3.3.3. Rheological Tests
The Amplitude Sweep
The Frequency Sweep
Dynamic Temperature Sweep Tests
Time Sweep Tests
3.3.4. In Vitro Diffusion Test—Frant Cell Test
- The TPC value for the polyphenols released in the 5 mL receptor chamber is mg/mL mg;
- The TPC value for the polyphenols’ releasing speed is mg/mL/t.
4. Discussion
4.1. Microbiological Control of Cosmetic Emulsions
4.2. Analysis of Homogeneity of the Emulsion
4.3. Rheological Measurements
The Amplitude Sweep
4.4. In Vitro Diffusion Test—Frant Cell Test
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Polyphenols Content, mg GAE/mL | Flavonoids Content, mg QE/mL | Antioxidant Activity | |
---|---|---|---|
DPPH (mg TE/mL) | ABTS (mg TE/mL) | ||
3.7986 | 4.490 | 0.21 ± 0.05 | 2.03 ± 0.12 |
Plant | Type of Extract | Polyphenol Content | Flavonoid Content | Ref. |
---|---|---|---|---|
Flowering aerial parts of A. oleracea | Solvent Methanol, Soxhlet extract | 1.38 GAE mg/g | 28.7 QE mg/g | [39] |
Leaf of A. oleracea | 80% ethanol (v/v), ultrasonic extraction | 3.19 mg GAE/g | 11.45 mg RE/g | [40] |
Flower of A. oleracea | 80% ethanol (v/v), Ultrasonic extraction | 1.98 mg GAE/g | 5.91 mg RE/g | [40] |
Dried extract of Flowering aerial parts of A. oleracea | Solvent Methanol, Soxhlet extract | 7.59 mg GAE/g of dried extract | indefinite | [19] |
Fresh leaves of A. oleracea | Solvent Methanol, Ultrasonic extraction, 30 min. | 588.65 mg GAE/100 g | 9.32 mg RE/100 g | [41] |
Fresh flower of A. oleracea | Solvent Methanol Ultrasonic extraction, 30 min. | 292.81 mg GAE/100 g | 4.10 mg RE/100 g | [41] |
Dried leaves of A. oleracea | Solvent Methanol Vortex extraction | 10.99 mg GAE/g | 11.33 mg RE/g | [42] |
Sample | Total Viable Microbiological Count, CFU/g | Total Viable Bacteria Count, CFU/g | Total Viable Yeast and Molds Count, CFU/g | Presence of Pathogenic Contaminants |
---|---|---|---|---|
Formulation 1 3% extract Acmella oleracea (F1A) | 10 | 10 | 10 | absent |
Formulation 2 5% extract Acmella oleracea (F2A) | 0 | 0 | 10 | absent |
Base (B1A) | 0 | 0 | 0 | absent |
Samples | Strain (ɣ = 0.1%) | |
---|---|---|
G’ (Pa) | G” (Pa) | |
B1A | 417 | 86 |
F1A | 671 | 159 |
F2A | 773 | 187 |
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Maxim, C.; Blaga, A.C.; Cimpoeșu, R.; Zinicovscaia, I.; Peshkova, A.; Danu, M.; Barna, A.S.; Suteu, D. Natural Antioxidants from Acmella oleracea Extract as Dermatocosmetic Actives. Sci. Pharm. 2024, 92, 52. https://doi.org/10.3390/scipharm92030052
Maxim C, Blaga AC, Cimpoeșu R, Zinicovscaia I, Peshkova A, Danu M, Barna AS, Suteu D. Natural Antioxidants from Acmella oleracea Extract as Dermatocosmetic Actives. Scientia Pharmaceutica. 2024; 92(3):52. https://doi.org/10.3390/scipharm92030052
Chicago/Turabian StyleMaxim, Claudia, Alexandra Cristina Blaga, Ramona Cimpoeșu, Inga Zinicovscaia, Alexandra Peshkova, Maricel Danu, Ana Simona Barna, and Daniela Suteu. 2024. "Natural Antioxidants from Acmella oleracea Extract as Dermatocosmetic Actives" Scientia Pharmaceutica 92, no. 3: 52. https://doi.org/10.3390/scipharm92030052