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Article

Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig

by
Faysal I. Mohammed
1,
Mohammed K. Al-Essa
1,
Yanal A. Shafagoj
1 and
Fatma U. Afifi
2,*
1
Department of Physiology and Biochemistry, Faculty of Medicine, University of Jordan
2
Pharmaceutical 2Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Queen Rania Street, 11942 Amman-Jordan
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2006, 74(1), 21-30; https://doi.org/10.3797/scipharm.2006.74.21
Submission received: 3 October 2005 / Accepted: 9 January 2006 / Published: 1 March 2006

Abstract

The effect of the ethanolic extract of Elaeagnus angustifolia was tested on dispersed smooth muscle cells (SMC) of the guinea pigs. A slight contractile response was observed when SMC were treated with low concentrations of the extract. Pre-treatment of the SMC with ethanolic extract of E. angustifolia caused concentration dependent inhibition of acetylcholine-induced contractions of the SMC.
Keywords: Elaeagnus angustifolia; dispersed smooth muscle cells; guinea pigs; acetylcholine Elaeagnus angustifolia; dispersed smooth muscle cells; guinea pigs; acetylcholine

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MDPI and ACS Style

Mohammed, F.I.; Al-Essa, M.K.; Shafagoj, Y.A.; Afifi, F.U. Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig. Sci. Pharm. 2006, 74, 21-30. https://doi.org/10.3797/scipharm.2006.74.21

AMA Style

Mohammed FI, Al-Essa MK, Shafagoj YA, Afifi FU. Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig. Scientia Pharmaceutica. 2006; 74(1):21-30. https://doi.org/10.3797/scipharm.2006.74.21

Chicago/Turabian Style

Mohammed, Faysal I., Mohammed K. Al-Essa, Yanal A. Shafagoj, and Fatma U. Afifi. 2006. "Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig" Scientia Pharmaceutica 74, no. 1: 21-30. https://doi.org/10.3797/scipharm.2006.74.21

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