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Applications for Marine Resources in Cosmetics

Cosmetic Potential of Marine Fish Skin Collagen

3B’s Research Group—Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark—Parque de Ciência e Tecnologia, 4805-017 Barco, Guimarães, Portugal
ICVS/3B’s—PT Government Associate Laboratory, Braga/Guimarães, Portugal
Author to whom correspondence should be addressed.
Cosmetics 2017, 4(4), 39;
Received: 19 September 2017 / Revised: 29 September 2017 / Accepted: 2 October 2017 / Published: 12 October 2017
(This article belongs to the Special Issue Cosmetics from Marine Sources)
Many cosmetic formulations have collagen as a major component because of its significant benefits as a natural humectant and moisturizer. This industry is constantly looking for innovative, sustainable, and truly efficacious products, so marine collagen based formulations are arising as promising alternatives. A solid description and characterization of this protein is fundamental to guarantee the highest quality of each batch. In the present study, we present an extensive characterization of marine-derived collagen extracted from salmon and codfish skins, targeting its inclusion as component in cosmetic formulations. Chemical and physical characterizations were performed using several techniques such as sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Fourier Transformation Infrared (FTIR) spectroscopy rheology, circular dichroism, X-ray diffraction, humidity uptake, and a biological assessment of the extracts regarding their irritant potential. The results showed an isolation of type I collagen with high purity but with some structural and chemical differences between sources. Collagen demonstrated a good capacity to retain water, thus being suitable for dermal applications as a moisturizer. A topical exposure of collagen in a human reconstructed dermis, as well as the analysis of molecular markers for irritation and inflammation, exhibited no irritant potential. Thus, the isolation of collagen from fish skins for inclusion in dermocosmetic applications may constitute a sustainable and low-cost platform for the biotechnological valorization of fish by-products. View Full-Text
Keywords: marine biomaterials; marine collagen; fish collagen; valorization of fish by-products moisturizer; cosmetic application marine biomaterials; marine collagen; fish collagen; valorization of fish by-products moisturizer; cosmetic application
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MDPI and ACS Style

Alves, A.L.; Marques, A.L.P.; Martins, E.; Silva, T.H.; Reis, R.L. Cosmetic Potential of Marine Fish Skin Collagen. Cosmetics 2017, 4, 39.

AMA Style

Alves AL, Marques ALP, Martins E, Silva TH, Reis RL. Cosmetic Potential of Marine Fish Skin Collagen. Cosmetics. 2017; 4(4):39.

Chicago/Turabian Style

Alves, Ana L., Ana L.P. Marques, Eva Martins, Tiago H. Silva, and Rui L. Reis 2017. "Cosmetic Potential of Marine Fish Skin Collagen" Cosmetics 4, no. 4: 39.

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