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Cosmetics 2015, 2(3), 248-258;

Thermal Behavior and Free-Radical-Scavenging Activity of Phytic Acid Alone and Incorporated in Cosmetic Emulsions

School of Pharmaceutical Sciences, University of São Paulo (FCF–USP), Av. Prof. Lineu Prestes, 580, Cidade Universitária, São Paulo 05508-000, Brazil
Chemistry Institute, University of São Paulo, Av. Prof. Lineu Prestes, 748, Cidade Universitária, São Paulo 05513-970, Brazil
Author to whom correspondence should be addressed.
Academic Editor: Martina Meinke
Received: 15 May 2015 / Revised: 15 July 2015 / Accepted: 21 July 2015 / Published: 31 July 2015
(This article belongs to the Special Issue The Antioxidant Potential of the Skin)
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Phytic acid is a natural compound widely used as depigmenting agent in cosmetic emulsions. Few studies are available in the literature covering the stability and the antioxidating property of this substance, used alone or into emulsions. Therefore, the purpose of this work was to investigate the thermal behavior and antioxidant properties of phytic acid alone and into cosmetic emulsions. The thermal behavior of this substance was evaluated by thermogravimetry (TG)/derivative thermogravimetry (DTG) and differential scanning calorimetry (DSC) and the free-radical-scavenging activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH). TG/DTG and DSC curves allowed evaluation of the thermal behavior of phytic acid. These results showed that the substance presented four stages of mass loss. Thermal decomposition of the material initiated at 150 °C. Thermal behavior of the cosmetic emulsions detected that the addition of phytic acid decreased the thermal stability of the system. DPPH free-radical-scavenging activity showed that phytic acid incorporated into emulsion had no antioxidant capacity compared to BHT. In summary, we concluded that the thermoanalytical techniques (TG and DSC) were efficient and reliable in the characterization of phytic acid alone and incorporated into cosmetic emulsions. View Full-Text
Keywords: phytic acid; cosmetic emulsions; thermal analysis; DPPH phytic acid; cosmetic emulsions; thermal analysis; DPPH

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Daneluti, A.L.M.; Velasco, M.V.R.; Baby, A.R.; Matos, J.D.R. Thermal Behavior and Free-Radical-Scavenging Activity of Phytic Acid Alone and Incorporated in Cosmetic Emulsions. Cosmetics 2015, 2, 248-258.

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