Next Article in Journal
Vesicular Trafficking Defects, Developmental Abnormalities, and Alterations in the Cellular Death Process Occur in Cell Lines that Over-Express Dictyostelium GTPase, Rab2, and Rab2 Mutants
Next Article in Special Issue
Regulated DNA Methylation and the Circadian Clock: Implications in Cancer
Previous Article in Journal / Special Issue
Control of Glycosylation-Related Genes by DNA Methylation: the Intriguing Case of the B3GALT5 Gene and Its Distinct Promoters
Open AccessReview

Preterm Birth and Its Long-Term Effects: Methylation to Mechanisms

1
Genetics and Molecular Biology Program, Emory University, Atlanta, GA 30322, USA
2
Department of Gynecology & Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA
3
Division of Maternal-Fetal Medicine Perinatal Research, Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA
4
The Perinatal Research Center, Nashville, TN 37203, USA
5
Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
*
Author to whom correspondence should be addressed.
Biology 2014, 3(3), 498-513; https://doi.org/10.3390/biology3030498
Received: 26 May 2014 / Revised: 8 August 2014 / Accepted: 12 August 2014 / Published: 21 August 2014
(This article belongs to the Special Issue DNA Methylation)
The epigenetic patterns established during development may influence gene expression over a lifetime and increase susceptibility to chronic disease. Being born preterm (<37 weeks of gestation) is associated with increased risk mortality and morbidity from birth until adulthood. This brief review explores the potential role of DNA methylation in preterm birth (PTB) and its possible long-term consequences and provides an overview of the physiological processes central to PTB and recent DNA methylation studies of PTB. View Full-Text
Keywords: DNA methylation; preterm birth; pregnancy; DOHaD; epigenetic; developmental programming; gestational age DNA methylation; preterm birth; pregnancy; DOHaD; epigenetic; developmental programming; gestational age
Show Figures

Figure 1

MDPI and ACS Style

Parets, S.E.; Bedient, C.E.; Menon, R.; Smith, A.K. Preterm Birth and Its Long-Term Effects: Methylation to Mechanisms. Biology 2014, 3, 498-513.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop