Deleterious Mutations in the Mitogenomes of Cetacean Populations
Round 1
Reviewer 1 Report
Comments and Suggestions for Authors-
Please clearly explain how the 2,244 mitochondrial genomes were specifically selected for this analysis. For example, mitochondrial genome data for Risso’s dolphin (Grampus griseus Cuvier, 1812) are available in public databases, yet this species does not appear in your analysis or results. The criteria for inclusion and exclusion of species must be clarified.
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The method used to identify low population sizes among different cetacean populations is not clearly described. Although several results are linked to low population size, the analytical approach or indicators used to infer this are insufficiently explained.
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Figure 6 consists of two panels; however, both panels use identical axis labels, which is misleading. Please revise the figure to clearly distinguish the variables presented in each panel.
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Figure 7 is not adequately explained. Although it contains two panels (A and B), their individual interpretations are missing. In particular, Panel A links mtDNA diversity with IUCN status, but the observation that medium-risk populations exhibit low mtDNA diversity is not sufficiently justified or discussed.
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Typically, the mitochondrial genome contains 13 protein-coding genes; however, only 12 genes were selected as “supergenes” in this study. The rationale for excluding one gene is unclear. Additionally, in line 96, the abbreviated gene names listed within brackets include only 11 genes, despite stating that 12 genes were used. This discrepancy must be corrected and clearly explained.
Although the English is clear, the manuscript requires further language polishing to meet professional academic standards.
Author Response
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Author Response File: 
Author Response.pdf
Reviewer 2 Report
Comments and Suggestions for Authorsfile is attached
Comments for author File: Comments.pdf
Author Response
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Author Response File: Author Response.pdf
