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Open AccessFeature PaperCommunication

Core/Shell Gel Beads with Embedded Halloysite Nanotubes for Controlled Drug Release

Dipartimento di Fisica e Chimica, Università degli Studi di Palermo, Viale delle Scienze, pad. 17, 90128 Palermo, Italy
Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali, INSTM, Via G. Giusti 9, I-50121 Firenze, Italy
Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml uramı 18, Kazan, Republic of Tatarstan 420008, Russia
Author to whom correspondence should be addressed.
Coatings 2019, 9(2), 70;
Received: 15 November 2018 / Revised: 14 January 2019 / Accepted: 22 January 2019 / Published: 24 January 2019
(This article belongs to the Special Issue Advanced Surface Coating of Nanoparticles)
The use of nanocomposites based on biopolymers and nanoparticles for controlled drug release is an attractive notion. We used halloysite nanotubes that were promising candidates for the loading and release of active molecules due to their hollow cavity. Gel beads based on chitosan with uniformly dispersed halloysite nanotubes were obtained by a dropping method. Alginate was used to generate a coating layer over the hybrid gel beads. This proposed procedure succeeded in controlling the morphology at the mesoscale and it had a relevant effect on the release profile of the model drug from the nanotube cavity. View Full-Text
Keywords: halloysite; alginate; chitosan; gel beads; drug release halloysite; alginate; chitosan; gel beads; drug release
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MDPI and ACS Style

Lisuzzo, L.; Cavallaro, G.; Parisi, F.; Milioto, S.; Fakhrullin, R.; Lazzara, G. Core/Shell Gel Beads with Embedded Halloysite Nanotubes for Controlled Drug Release. Coatings 2019, 9, 70.

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