Next Article in Journal
Synthesis and Characterization of Ni–W/Cr2O3 Nanocomposite Coatings Using Electrochemical Deposition Technique
Previous Article in Journal
Investigation of the Microwave Absorption of Asphalt Mixtures Containing Magnetite Powder
Previous Article in Special Issue
Hydrophobic and Icephobic Behaviour of Polyurethane-Based Nanocomposite Coatings
Open AccessArticle

Aging of Solvent-Casting PLA-Mg Hydrophobic Films: Impact on Bacterial Adhesion and Viability

Department of Applied Physics, University of Extremadura, 06006 Badajoz, Spain
Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 06006 Badajoz, Spain
University Institute of Extremadura Sanity Research (iNube), 06006 Badajoz, Spain
Author to whom correspondence should be addressed.
Coatings 2019, 9(12), 814;
Received: 31 October 2019 / Revised: 25 November 2019 / Accepted: 29 November 2019 / Published: 2 December 2019
(This article belongs to the Special Issue Low-Adhesion Coatings: Fundamentals and Applications)
Biomaterials used for the manufacture of biomedical devices must have suitable surface properties avoiding bacterial colonization and/or proliferation. Most biomaterial-related infections start during the surgery. Bacteria can begin colonization of the surface of a device right after implantation or in the next few hours. This time may also be sufficient to begin the deterioration of a biodegradable implant. This work explores the surface changes that hydrophobic films of poly(lactic) acid reinforced with Mg particles, prepared by solving-casting, undergone after in vitro degradation at different times. Hydrophobicity, surface tension, zeta potential, topography, and elemental composition were obtained from new and aged films. The initial degradation for 4 h was combined with unspecific bacterial adhesion and viability tests to check if degraded films are more or less susceptible to be contaminated. The degradation of the films decreases their hydrophobicity and causes the appearance of a biocompatible layer, composed mainly of magnesium phosphate. The release of Mg2+ is very acute at the beginning of the degradation process, and such positive charges may favor the electrostatic approach and attachment of Staphylococci. However, all bacteria attached on the films containing Mg particles appeared damaged, ensuring the bacteriostatic effect of these films, even after the first hours of their degradation. View Full-Text
Keywords: poly(lactic) acid; hydrophobicity; solvent-casting; S. epidermidis; bacterial adhesion poly(lactic) acid; hydrophobicity; solvent-casting; S. epidermidis; bacterial adhesion
Show Figures

Figure 1

MDPI and ACS Style

Luque-Agudo, V.; Romero-Guzmán, D.; Fernández-Grajera, M.; González-Martín, M.L.; Gallardo-Moreno, A.M. Aging of Solvent-Casting PLA-Mg Hydrophobic Films: Impact on Bacterial Adhesion and Viability. Coatings 2019, 9, 814.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop