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Prevention of Periodontitis by the Addition of a Bactericidal Particulate Glass/Glass-Ceramic to a Dental Resin: A Pilot Study in Dogs

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Nanomaterials and Nanotechnology Research Center (CINN-CSIC), Universidad de Oviedo (UO), Principado de Asturias, Avda. de la Vega 4-6, 33940 El Entrego, Spain
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Nanoker Research, Pol. Ind., Olloniego, Parcela 22A, Nave 5, 33660 Oviedo, Spain
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Author to whom correspondence should be addressed.
Coatings 2018, 8(8), 259; https://doi.org/10.3390/coatings8080259
Received: 27 June 2018 / Revised: 12 July 2018 / Accepted: 22 July 2018 / Published: 25 July 2018
(This article belongs to the Special Issue Advances in Functional Inorganic Coatings)
The aim of the study is to evaluate, in a ligature-induced periodontitis model, the efficacy of a commercially available dental resin containing different antimicrobial glass/glass-ceramic additions (0–26 wt.%). It has been proved that a 26 wt.% glass addition to a conventional dental resin matrix does not alter neither its workability nor its adhesion to the surface of teeth; however, it does confer notable antimicrobial properties when tested in vitro. Moreover, in vivo tests in Beagle dogs demonstrated the prevention of bone loss in ligature-induced plaque accumulation around teeth. Particularly, the glass-ceramic filler resin composite has shown excellent antimicrobial control since it displays the same bone loss as that of the negative control. The results obtained in the present investigation have shown that a conventional dental resin containing a fraction of glass/glass-ceramic (≥26 wt.%) can prevent periodontitis, which is considered to be a most serious dental disease. View Full-Text
Keywords: periodontitis; bactericidal glass/glass-ceramic; dental materials; dental composites periodontitis; bactericidal glass/glass-ceramic; dental materials; dental composites
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López-Píriz, R.; Díaz, L.A.; Cabal, B.; Fernández, A.; Suárez, M.; Díaz, R.; Torrecillas, R.; Moya, J.S. Prevention of Periodontitis by the Addition of a Bactericidal Particulate Glass/Glass-Ceramic to a Dental Resin: A Pilot Study in Dogs. Coatings 2018, 8, 259.

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