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Structure, Formation, and Biological Interactions of Supported Lipid Bilayers (SLB) Incorporating Lipopolysaccharide

Department of Chemistry and Biochemistry, University of Missouri—Saint Louis, Saint Louis, MO 63121, USA
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Coatings 2020, 10(10), 981; https://doi.org/10.3390/coatings10100981
Received: 24 August 2020 / Revised: 5 October 2020 / Accepted: 12 October 2020 / Published: 14 October 2020
(This article belongs to the Section Bioactive Coatings and Biointerfaces)
Biomimetic membrane systems play a crucial role in the field of biosensor engineering. Over the years, significant progress has been achieved creating artificial membranes by various strategies from vesicle fusion to Langmuir transfer approaches to meet an ever-growing demand for supported lipid bilayers on various substrates such as glass, mica, gold, polymer cushions, and many more. This paper reviews the diversity seen in the preparation of biologically relevant model lipid membranes which includes monolayers and bilayers of phospholipid and other crucial components such as proteins, characterization techniques, changes in the physical properties of the membranes during molecular interactions and the dynamics of the lipid membrane with biologically active molecules with special emphasis on lipopolysaccharides (LPS). View Full-Text
Keywords: Langmuir–Blodgett; lipopolysaccharides; supported bilayers; monolayers Langmuir–Blodgett; lipopolysaccharides; supported bilayers; monolayers
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MDPI and ACS Style

Sondhi, P.; Lingden, D.; Stine, K.J. Structure, Formation, and Biological Interactions of Supported Lipid Bilayers (SLB) Incorporating Lipopolysaccharide. Coatings 2020, 10, 981.

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