Medical-Grade Honey Kills Antibiotic-Resistant Bacteria and Prevents Amputation in Diabetics with Infected Ulcers: A Prospective Case Series
Abstract
:1. Introduction
2. Results
2.1. Case 1
2.2. Case 2
2.3. Case 3
2.4. Case 4
2.5. Case 5
2.6. Case 6
3. Discussion
4. Materials and Methods
4.1. Subjects and therapeutic interventions
4.2. About L-Mesitran wound care products
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Case | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|
t Infection | 4 weeks | 1 week | 3 weeks | 3 weeks | 3 weeks | 2 weeks |
t Granulation | 4 weeks | 4 weeks | 3 weeks | 3 weeks | 3 weeks | 3 weeks |
t Healing | 52 weeks | 32 weeks | 10 weeks | 12 weeks | 6 weeks | 7 weeks |
Risk Amputation | Yes | Yes | Yes | Yes |
Case | Initial 1° Dressing | Initial 2° Dressing | Duration and Dressing Regime | 1° Dressing Treatment Change | 2° Dressing Treatment Change | Duration and Dressing Regime |
---|---|---|---|---|---|---|
1 | Soft and Net | Sterile absorptive gauzes | 4 weeks of daily changes | Soft | Sterile absorptive gauzes | 48 weeks of daily changes following weekly application |
2 | Ointment and Net | Sterile absorptive gauzes | 2 months of two changes per day | Soft | Sterile absorptive gauzes | 6 months of daily changes |
3 | Ointment and Hydro | Fixative gauzes | 7 weeks of daily changes | Soft and Tulle | Sterile absorptive gauzes | 3 weeks of daily changes |
4 | Ointment | Film dressing | 2 weeks of daily changes | Ointment | Alginate and film dressing | 10 weeks of daily changes |
5 | Ointment | Film dressing | 6 weeks of daily changes | |||
6 | Ointment and Net | Sterile absorptive gauzes | 3 weeks of daily changes | Soft and Tulle | Sterile absorptive gauzes | 3 weeks of daily changes |
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Nair, H.K.R.; Tatavilis, N.; Pospíšilová, I.; Kučerová, J.; Cremers, N.A.J. Medical-Grade Honey Kills Antibiotic-Resistant Bacteria and Prevents Amputation in Diabetics with Infected Ulcers: A Prospective Case Series. Antibiotics 2020, 9, 529. https://doi.org/10.3390/antibiotics9090529
Nair HKR, Tatavilis N, Pospíšilová I, Kučerová J, Cremers NAJ. Medical-Grade Honey Kills Antibiotic-Resistant Bacteria and Prevents Amputation in Diabetics with Infected Ulcers: A Prospective Case Series. Antibiotics. 2020; 9(9):529. https://doi.org/10.3390/antibiotics9090529
Chicago/Turabian StyleNair, Harikrishna K. R., Nektarios Tatavilis, Ivana Pospíšilová, Jana Kučerová, and Niels A. J. Cremers. 2020. "Medical-Grade Honey Kills Antibiotic-Resistant Bacteria and Prevents Amputation in Diabetics with Infected Ulcers: A Prospective Case Series" Antibiotics 9, no. 9: 529. https://doi.org/10.3390/antibiotics9090529