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Open AccessReview

Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?

1
UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, Australia
2
2nd Critical Care Department, ‘Attikon’ University Hospital, Athens 11632, Greece
3
Department of Critical Care Medicine, ‘Papageorgiou’ General Hospital of Thessaloniki, Thessaloniki 56429, Greece
4
Department of Intensive Care Medicine, Royal Brisbane and Women’s Hospital, Brisbane 4029, Australia
5
Royal Brisbane Clinical Unit, Faculty of Medicine, The University of Queensland, Brisbane 4029, Australia
*
Author to whom correspondence should be addressed.
Equal contribution (2nd authors).
Antibiotics 2020, 9(2), 51; https://doi.org/10.3390/antibiotics9020051
Received: 30 December 2019 / Revised: 26 January 2020 / Accepted: 29 January 2020 / Published: 31 January 2020
Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration? View Full-Text
Keywords: ventilator-associated tracheobronchitis; VAT; diagnosis; treatment; inhaled antibiotics ventilator-associated tracheobronchitis; VAT; diagnosis; treatment; inhaled antibiotics
MDPI and ACS Style

Koulenti, D.; Arvaniti, K.; Judd, M.; Lalos, N.; Tjoeng, I.; Xu, E.; Armaganidis, A.; Lipman, J. Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? Antibiotics 2020, 9, 51.

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