Next Article in Journal
A Mini-Review on Ceftaroline in Bacteremia Patients with Methicillin-Resistant Staphylococcus aureus (MRSA) Infections
Previous Article in Journal
Antibiotic Activity Potentiation and Physicochemical Characterization of the Fixed Orbignya speciosa Almond Oil against MDR Staphylococcus aureus and Other Bacteria
Open AccessReview

Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review

1
Department of Global Health, Research School of Population Health, Australian National University, Canberra ACT 2600, Australia
2
Diagnostic Microbiology Development Program, Phnom Penh 12000, Cambodia
3
Médecins Sans Frontières, 1202 Geneva, Switzerland
*
Author to whom correspondence should be addressed.
Antibiotics 2019, 8(1), 29; https://doi.org/10.3390/antibiotics8010029
Received: 26 February 2019 / Revised: 13 March 2019 / Accepted: 14 March 2019 / Published: 19 March 2019
Several studies have investigated antimicrobial resistance in low- and middle-income countries, but to date little attention has been paid to the Pacific Islands Countries and Territories (PICTs). This study aims to review the literature on antibiotic resistance (ABR) in healthcare settings in PICTs to inform further research and future policy development for the region. Following the PRISMA-ScR checklist health databases and grey literature sources were searched. Three reviewers independently screened the literature for inclusion, data was extracted using a charting tool and the results were described and synthesised. Sixty-five studies about ABR in PICTs were identified and these are primarily about New Caledonia, Fiji and Papua New Guinea. Ten PICTs contributed the remaining 21 studies and nine PICTs were not represented. The predominant gram-positive pathogen reported was community-acquired methicillin resistant S. aureus and the rates of resistance ranged widely (>50% to <20%). Resistance reported in gram-negative pathogens was mainly associated with healthcare-associated infections (HCAIs). Extended spectrum beta-lactamase (ESBL) producing K. pneumoniae isolates were reported in New Caledonia (3.4%) and Fiji (22%) and carbapenem resistant A. baumannii (CR-ab) isolates in the French Territories (24.8%). ABR is a problem in the PICTs, but the epidemiology requires further characterisation. Action on strengthening surveillance in PICTs needs to be prioritised so strategies to contain ABR can be fully realised. View Full-Text
Keywords: antimicrobial resistance; gram-negative organisms; gram-positive organisms; surveillance; healthcare associated infections antimicrobial resistance; gram-negative organisms; gram-positive organisms; surveillance; healthcare associated infections
Show Figures

Figure 1

MDPI and ACS Style

Foxlee, N.D.; Townell, N.; McIver, L.; Lau, C.L. Antibiotic Resistance in Pacific Island Countries and Territories: A Systematic Scoping Review. Antibiotics 2019, 8, 29.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop