Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. Bacterial Strains: Collection and Identification
4.2. Antimicrobial Susceptibility Testing
4.3. Molecular Typing
4.4. Whole-Genome Sequencing (WGS)
4.5. Plasmid Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Isolate (n°) | Isolation Date | Pulse Type | bla | Source | Hospital | cgMLST | Capsule Type | Plasmids | |
---|---|---|---|---|---|---|---|---|---|
ESBL 1 | CPase 2 | ||||||||
2017787 | 14 August 2017 | P1 | CTX-M-15 | VIM-1 | Bloodstream | Infanta Elena | 3266 | KL64/O2v1 | IncR, ColpVC |
2017917 | 15 September 2017 | P1 | CTX-M-15 | VIM-1 | Urine | Infanta Elena | N.A 3 | N.A | |
20180256 | 16 March 2018 | P2 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | 3266 | KL64/O2v1 | IncR, ColpVC |
20180516 | 24 May 2018 | P2 | CTX-M-15 | VIM-1 | Bloodstream | Infanta Elena | N.A | N.A | |
20180784 | 5 September 2018 | P3 | CTX-M-15 | VIM-1 | Skin and soft tissues | Infanta Elena | N.A | N.A | |
20180797 | 15 September 2018 | P3 | CTX-M-15 | VIM-1 | Skin and soft tissues | Infanta Elena | N.A | N.A | |
20180912 | 5 October 2018 | P3 | CTX-M-15 | VIM-1 | Rectal swab | Infanta Elena | 3266 | KL64/O2v1 | IncR, ColpVC |
20181086 | 29 November 2018 | P1 | CTX-M-15 | VIM-1 | Urine | Infanta Elena | N.A | N.A | |
20181087 | 30 November 2018 | P1 | CTX-M-15 | VIM-1 | Rectal swab | Infanta Elena | N.A | N.A | |
20181130 | 13 December 2018 | P4 | CTX-M-15 | VIM-1 | Bloodstream | Virgen Macarena | 3266 | KL64/O2v1 | IncR, ColpVC |
20190090 | 31 January 2019 | P5 | CTX-M-15 | VIM-1 | Respiratory | Juan Ramón Jimenez | 3266 | KL64/O2v1 | IncR, ColpVC |
20190095 | 7 February 2019 | P6 | CTX-M-15 | VIM-1 | Urine | Juan Ramón Jimenez | 3266 | KL64/O2v1 | IncR, ColpVC |
20190096 | 13 February 2019 | P7 | CTX-M-15 | VIM-1 | Urine | Virgen Macarena | N.A 3 | N.A | |
20190175 | 13 March 2019 | P4 | CTX-M-15 | VIM-1 | Urine | Virgen Macarena | N.A | N.A | |
20190191 | 22 February 2019 | P7 | CTX-M-15 | VIM-1 | Respiratory | Juan Ramón Jimenez | 3266 | KL64/O2v1 | IncR, ColpVC |
20190260 | 2 May 2019 | P4 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190268 | 7 May 2019 | P5 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190286 | 12 May 2019 | P7 | CTX-M-15 | VIM-1 | Bloodstream | Virgen Macarena | N.A | N.A | |
20190303 | 17 May 2019 | P4 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190402 | 1 July 2019 | P7 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190403 | 1 July 2019 | P7 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190504 | 24 July 2019 | P4 | CTX-M-15 | VIM-1 | Skin and soft tissues | Virgen Macarena | N.A | N.A | |
20190523 | 14 August 2019 | P4 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190524 | 14 August 2019 | P4 | CTX-M-15 | VIM-1 | Rectal swab | Virgen Macarena | N.A | N.A | |
20190526 | 14 August 2019 | P7 | CTX-M-15 | VIM-1 | Skin and soft tissues | Virgen Macarena | N.A 3 | N.A | |
20190643 | 5 September 2019 | P2 | CTX-M-15 | VIM-1 | Respiratory | Infanta Elena | 5114 | KL64/O2v1 | IncR, ColpVC |
20190693 | 24 September 2019 | P5 | CTX-M-15 | VIM-1 | Skin and soft tissues | De la Merced | N.A | N.A | |
20190717 | 14 October 2019 | P7 | CTX-M-15 | VIM-1 | Urine | Virgen Macarena | N.A | N.A | |
20190944 | 20 December 2019 | P5 | CTX-M-15 | VIM-1 | Urine | Virgen Macarena | N.A | N.A |
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Pérez-Palacios, P.; Gual-de-Torrella, A.; Portillo-Calderón, I.; Recacha-Villamor, E.; Franco-Álvarez de Luna, F.; Lopez-Cerero, L.; Pascual, A. Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain. Antibiotics 2023, 12, 1727. https://doi.org/10.3390/antibiotics12121727
Pérez-Palacios P, Gual-de-Torrella A, Portillo-Calderón I, Recacha-Villamor E, Franco-Álvarez de Luna F, Lopez-Cerero L, Pascual A. Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain. Antibiotics. 2023; 12(12):1727. https://doi.org/10.3390/antibiotics12121727
Chicago/Turabian StylePérez-Palacios, Patricia, Ana Gual-de-Torrella, Ines Portillo-Calderón, Esther Recacha-Villamor, Francisco Franco-Álvarez de Luna, Lorena Lopez-Cerero, and Alvaro Pascual. 2023. "Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain" Antibiotics 12, no. 12: 1727. https://doi.org/10.3390/antibiotics12121727
APA StylePérez-Palacios, P., Gual-de-Torrella, A., Portillo-Calderón, I., Recacha-Villamor, E., Franco-Álvarez de Luna, F., Lopez-Cerero, L., & Pascual, A. (2023). Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain. Antibiotics, 12(12), 1727. https://doi.org/10.3390/antibiotics12121727