Next Article in Journal
Clonal Diversity of Klebsiella spp. and Escherichia spp. Strains Isolated from Patients with Ventilator-Associated Pneumonia
Next Article in Special Issue
Antimicrobial Resistance Profiles and Genetic Typing of Salmonella Serovars from Chicken Embryos in China
Previous Article in Journal
Advances in Bacteriophage Therapy against Relevant MultiDrug-Resistant Pathogens
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Antibiotics
Volume 10
Issue 6
10.3390/antibiotics10060673
antibiotics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Association of Antimicrobial Resistance in Campylobacter spp. in Broilers and Turkeys with Antimicrobial Use

by
Bernd-Alois Tenhagen
1,*,
Matthias Flor
1,
Katja Alt
1,
Marie-Theres Knüver
2,
Christiane Buhler
2,
Annemarie Käsbohrer
1 and
Kerstin Stingl
2
1
Unit Epidemiology, Zoonoses and Antimicrobial Resistance, Department Biological Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8–10, 10589 Berlin, Germany
2
Unit Food Microbiology, Pathogen-Host Interactions, Department Biological Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8–10, 10589 Berlin, Germany
*
Author to whom correspondence should be addressed.
Antibiotics 2021, 10(6), 673; https://doi.org/10.3390/antibiotics10060673
Submission received: 14 April 2021 / Revised: 27 May 2021 / Accepted: 29 May 2021 / Published: 4 June 2021
(This article belongs to the Special Issue Antimicrobial Resistance and Zoonoses)
Versions Notes

Abstract

We investigated trends in antimicrobial resistance (AMR) in Campylobacter jejuni and Campylobacter coli in poultry between 2010 and 2016 in Germany and their association with antimicrobial use. Campylobacter had been isolated from the caeca of broilers and turkeys at slaughter by regional laboratories according to current ISO methods in the framework of a national monitoring program. Isolates were submitted to the National Reference Laboratory for Campylobacter and tested for AMR using broth microdilution methods. Minimum inhibitory concentrations were evaluated according to epidemiological cut-off values. Antimicrobial use (AMU) data from 2014 to 2016 were taken from a government report. AMR was higher in C. coli than in C. jejuni and higher in turkeys than in broilers. AMR was highest to tetracycline and the tested (fluoro)quinolones while it was rare to gentamicin in both bacterial species, infrequent to erythromycin in C. jejuni, and moderate in C. coli. AMR to tetracycline and erythromycin decreased over time while it increased to (fluoro)quinolones. An association of AMU and AMR was observed for resistance to tetracycline and erythromycin, while it was not observed for the aminoglycosides. Resistance to nalidixic acid and ciprofloxacin increased despite a decrease of fluoroquinolone use between 2014 and 2016, indicating that other factors have a strong influence on resistance to (fluoro)quinolones in Campylobacter.
Keywords: Campylobacter; antimicrobial resistance; antimicrobial use; poultry Campylobacter; antimicrobial resistance; antimicrobial use; poultry

Share and Cite

MDPI and ACS Style

Tenhagen, B.-A.; Flor, M.; Alt, K.; Knüver, M.-T.; Buhler, C.; Käsbohrer, A.; Stingl, K. Association of Antimicrobial Resistance in Campylobacter spp. in Broilers and Turkeys with Antimicrobial Use. Antibiotics 2021, 10, 673. https://doi.org/10.3390/antibiotics10060673

AMA Style

Tenhagen B-A, Flor M, Alt K, Knüver M-T, Buhler C, Käsbohrer A, Stingl K. Association of Antimicrobial Resistance in Campylobacter spp. in Broilers and Turkeys with Antimicrobial Use. Antibiotics. 2021; 10(6):673. https://doi.org/10.3390/antibiotics10060673

Chicago/Turabian Style

Tenhagen, Bernd-Alois, Matthias Flor, Katja Alt, Marie-Theres Knüver, Christiane Buhler, Annemarie Käsbohrer, and Kerstin Stingl. 2021. "Association of Antimicrobial Resistance in Campylobacter spp. in Broilers and Turkeys with Antimicrobial Use" Antibiotics 10, no. 6: 673. https://doi.org/10.3390/antibiotics10060673

APA Style

Tenhagen, B.-A., Flor, M., Alt, K., Knüver, M.-T., Buhler, C., Käsbohrer, A., & Stingl, K. (2021). Association of Antimicrobial Resistance in Campylobacter spp. in Broilers and Turkeys with Antimicrobial Use. Antibiotics, 10(6), 673. https://doi.org/10.3390/antibiotics10060673

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop