Using Graphene-Based Biosensors to Detect Dopamine for Efficient Parkinson’s Disease Diagnostics
Abstract
:1. Introduction
2. Analytical Performances of DA Graphene-Based Biosensors
3. Challenges and Perspectives towards POC Diagnostics of DA
4. Conclusions and Viewpoint
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Graphene Functionalization | LOD (μM) | Biological Samples | Interference Compound | Reference |
---|---|---|---|---|
3D RGO-PU | 1.0 × 10−6 | (h) urine, serum | AA, UA, Glu, CA, 4-NP, Trp, Tyr, GSH | [30] |
PFSG/GCE | 0.0008 | (h) serum | AA, UA | [31] |
ZnO NWAs/GF | 0.001 | (PD) serum | AA, UA | [32] |
NiAl LDH/G LBL | 0.002 | SH-SY 5Y cells | AA, UA | [33] |
Au NPs-CNT-G-pMet-SPCE | 0.0029 | (h) urine | UA | [7] |
AgNCs/AgNPs/GO | 0.00353 | brain homogenate of PD mice | GSH | [34] |
GR/GLN | 0.0045 | (h) urine, serum | AA, UA, Glu | [35] |
Fe3O4/rGO/GCE | 0.005 | (h) urine | UA, CA, Glu, AA, NaCl, AP | [36] |
Fe3O4@GNs/Nafion/GCE | 0.00713 | (h) urine, plasma | AA, UA | [37] |
graphene-MoS2/GCE | 0.007 | (b) serum | AA, UA, CA, Glu, cysteine, Na+, K+, Mg2+, Ca2+, Cl− | [38] |
Fe3O4-SnO2-G/CPE | 0.0071 | (h) urine, serum | AA, UA | [39] |
RGO/Mn-TPP/GCE | 0.008 | (h) serum | AA, UA | [40] |
Ag NPs/GO/P(Arg)/GCE | 0.01 | (h) urine | U, CA, Glu, Na+, K+, L-lysine, L-cysteine | [41] |
TiN-RGO/GCE | 0.012 | (h) urine | AA, UA, Glu, LA | [42] |
PA/GO/GCE | 0.016 | (h) urine | AA, UA | [43] |
GNCs/CMG/GCE | 0.02 | (h) serum | AA | [44] |
Au–Pt/GO–ERGO | 0.0207 | (h) serum | AA, 5-HT, UA, AP, EP, NEP, CA, Glu, H2O2, NaCl, KCl, KNO3, Na2SO4, ZnCl2, CaCl2, (b) serum albumin, immunoglobulin | [45] |
α-Fe2O3@erGO/GCE | 0.024 | (h) serum | AA, UA, Glu, U, H2O2, NaCl, KCl | [46] |
CNDs-RGO/GCE | 0.03 | (h) serum | UA | [47] |
Au-ZnO NCAs/GF | 0.04 | (h) urine | UA | [48] |
Pt/rGO/MEA | 0.05 | (r) CPU | AA, UA, Glu, U, 5-HT, DOPAC | [49] |
rGO–Cu2O/GCE | 0.05 | (h) urine, blood | AA, UA | [50] |
PANI/Fe2O3-SnO2/rGO/PFSG/GCE | 0.076 | (a) urine | UA | [27] |
PTPCNs/GCE | 0.078 | DA injection and urine | UA | [51] |
ERGO/PLL/GCE | 0.10 | (h) urine | AA, UA | [52] |
3D-NG | 0.26 | (h) urine | AA, UA, AP | [53] |
GO/Au NPs | 0.29 | (a) urine | UA, AA | [20] |
AG-NA/GCE | 0.33 | (h) urine | AP | [54] |
GO-BAMB-Co(OH)2 | 0.4 | (h) urine | AA, 5-HT | [55] |
Pd-GR/nano-CILE | 0.5 | (h) urine, serum | UA | [56] |
3D HGB/ITO | 1.0 * | (h) plasma | UA | [57] |
Pdop@GR/MWCNTs | 1.0 | (h) urine, serum | AA, UA | [58] |
RGO–ZnO/GCE | 1.08 | (h) urine, plasma | AA, UA | [59] |
Au/RGO/GCE | 1.4 | (r) serum | AA, UA, CA, NaCl, KCl, NaNO3, CaCl2, Glu, cysteine | [60] |
mp-GR/GCE | 1.5 | (h) serum | UA | [61] |
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Kujawska, M.; Bhardwaj, S.K.; Mishra, Y.K.; Kaushik, A. Using Graphene-Based Biosensors to Detect Dopamine for Efficient Parkinson’s Disease Diagnostics. Biosensors 2021, 11, 433. https://doi.org/10.3390/bios11110433
Kujawska M, Bhardwaj SK, Mishra YK, Kaushik A. Using Graphene-Based Biosensors to Detect Dopamine for Efficient Parkinson’s Disease Diagnostics. Biosensors. 2021; 11(11):433. https://doi.org/10.3390/bios11110433
Chicago/Turabian StyleKujawska, Małgorzata, Sheetal K. Bhardwaj, Yogendra Kumar Mishra, and Ajeet Kaushik. 2021. "Using Graphene-Based Biosensors to Detect Dopamine for Efficient Parkinson’s Disease Diagnostics" Biosensors 11, no. 11: 433. https://doi.org/10.3390/bios11110433