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Design, Fabrication, and Implementation of a Wireless, Passive Implantable Pressure Sensor Based on Magnetic Higher-Order Harmonic Fields

Department of Biomedical Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA
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Biosensors 2011, 1(4), 134-152; https://doi.org/10.3390/bios1040134
Received: 11 August 2011 / Revised: 2 October 2011 / Accepted: 14 October 2011 / Published: 17 October 2011
A passive and wireless sensor was developed for monitoring pressure in vivo. Structurally, the pressure sensor, referred to as the magneto-harmonic pressure sensor, is an airtight chamber sealed with an elastic pressure membrane. A strip of magnetically-soft material is attached to the bottom of the chamber and a permanent magnet strip is embedded inside the membrane. Under the excitation of an externally applied AC magnetic field, the magnetically-soft strip produces a higher-order magnetic signature that can be remotely detected with an external receiving coil. As ambient pressure varies, the pressure membrane deflects, altering the separation distance between the magnetically-soft strip and the permanent magnet. This shifts the higher-order harmonic signal, allowing for detection of pressure change as a function of harmonic shifting. The wireless, passive nature of this sensor technology allows for continuous long-term pressure monitoring, particularly useful for biomedical applications such as monitoring pressure in aneurysm sac and sphincter of Oddi. In addition to demonstrating its pressure sensing capability, an animal model was used to investigate the efficacy and feasibility of the pressure sensor in a biological environment. View Full-Text
Keywords: biomedical instruments; biosensors; higher-order harmonic fields; implantable sensors; magnetic detection; noninvasive monitoring; passive; pressure; soft magnetic materials; wireless sensors biomedical instruments; biosensors; higher-order harmonic fields; implantable sensors; magnetic detection; noninvasive monitoring; passive; pressure; soft magnetic materials; wireless sensors
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Tan, E.L.; DeRouin, A.J.; Pereles, B.D.; Ong, K.G. Design, Fabrication, and Implementation of a Wireless, Passive Implantable Pressure Sensor Based on Magnetic Higher-Order Harmonic Fields. Biosensors 2011, 1, 134-152.

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