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Research Progress of M13 Bacteriophage-Based Biosensors

1
National Core Research Center for Hybrid Materials Solution, Pusan National University, Busan 46241, Korea
2
Department of BIT Fusion Technology Center, Pusan National University, Busan 46241, Korea
3
Department of Public Health Sciences, Graduate School, Korea University, Seoul 02708, Korea
4
Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, Korea
5
Department of Nanofusion Technology, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, Korea
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Nanomaterials 2019, 9(10), 1448; https://doi.org/10.3390/nano9101448 (registering DOI)
Received: 3 September 2019 / Revised: 2 October 2019 / Accepted: 3 October 2019 / Published: 11 October 2019
(This article belongs to the Special Issue Virus-Based Nanomaterials and Nanostructures)
Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.
Keywords: virus; biosensor; M13 bacteriophage; color sensor; phage display virus; biosensor; M13 bacteriophage; color sensor; phage display
MDPI and ACS Style

Moon, J.-S.; Choi, E.J.; Jeong, N.-N.; Sohn, J.-R.; Han, D.-W.; Oh, J.-W. Research Progress of M13 Bacteriophage-Based Biosensors. Nanomaterials 2019, 9, 1448.

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