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Nanomaterials 2018, 8(8), 627; https://doi.org/10.3390/nano8080627

Biosynthesis of Silver Nanoparticles Using Ligustrum Ovalifolium Fruits and Their Cytotoxic Effects

1
Research Center for Advanced Chemical Analysis, Instrumentation and Chemometrics (ANALYTICA), Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos Street, Cluj-Napoca 400028, Romania
2
Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos Street, Cluj-Napoca 400028, Romania
3
“Ion Chiricuta” Oncology Institute, 34–36 Republicii Street, Cluj-Napoca 400015, Romania
*
Author to whom correspondence should be addressed.
Received: 16 July 2018 / Revised: 14 August 2018 / Accepted: 17 August 2018 / Published: 18 August 2018
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Abstract

The present study reports for the first time the efficacy of bioactive compounds from Ligustrum ovalifolium L. fruit extract as reducing and capping agents of silver nanoparticles (AgNPs), developing a green, zero energetic, cost effective and simple synthesis method of AgNPs. The obtained nanoparticles were characterized by UV-Vis spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier Transform Infrared spectroscopy (FTIR), confirming that nanoparticles were crystalline in nature, spherical in shape, with an average size of 7 nm. The FTIR spectroscopy analysis demonstrated that the AgNPs were capped and stabilized by bioactive molecules from the fruit extract. The cytotoxicity of the biosynthesized AgNPs was in vitro evaluated against ovarian carcinoma cells and there were found to be effective at low concentration levels. View Full-Text
Keywords: phytosynthesis; silver nanoparticles; Ligustrum ovalifolium L.; cytotoxic activity; ovarian carcinoma cells phytosynthesis; silver nanoparticles; Ligustrum ovalifolium L.; cytotoxic activity; ovarian carcinoma cells
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Moldovan, B.; Sincari, V.; Perde-Schrepler, M.; David, L. Biosynthesis of Silver Nanoparticles Using Ligustrum Ovalifolium Fruits and Their Cytotoxic Effects. Nanomaterials 2018, 8, 627.

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