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Lanthanide-Doped Nanoparticles for Diagnostic Sensing

by 1, 2,3, 4,5 and 1,*
School of Chemical Engineering, Chonnam National University, Gwangju 61186, Korea
The Key Laboratory of Biomedical Information Engineering, Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China
Bioinspired Engineering and Biomechanics Center (BEBC), Xi’an Jiaotong University, Xi’an 710049, China
International Research Organization for Advance Science and Technology (IROAST), Kumamoto University, Kumamoto 860-8555, Japan
Magnesium Research Center, Kumamoto University, Kumamoto 860-8555, Japan
Author to whom correspondence should be addressed.
Nanomaterials 2017, 7(12), 411;
Received: 9 October 2017 / Revised: 15 November 2017 / Accepted: 20 November 2017 / Published: 23 November 2017
(This article belongs to the Special Issue Nanomaterials for Sensing Applications)
Lanthanide-doped nanoparticles exhibit unique optical properties, such as a long luminescence lifetime (up to several milliseconds), sharp emission peaks, and upconversion luminescence over the range of wavelengths from near-infrared to visible. Exploiting these optical properties, lanthanide-doped nanoparticles have been widely utilized for cellular and small animal imaging with the absence of background autofluorescence. In addition, these nanoparticles have advantages of high signal-to-noise ratio for highly sensitive and selective diagnostic detection. In this review, we summarize and discuss recent progress in the development of highly sensitive diagnostic methods using lanthanide-doped nanoparticles. Combined with a smartphone, portable luminescence detecting platforms could be widely applied in point-of-care tests. View Full-Text
Keywords: lanthanide; upconversion; nanoparticles; diagnostics; sensing lanthanide; upconversion; nanoparticles; diagnostics; sensing
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MDPI and ACS Style

Lee, S.Y.; Lin, M.; Lee, A.; Park, Y.I. Lanthanide-Doped Nanoparticles for Diagnostic Sensing. Nanomaterials 2017, 7, 411.

AMA Style

Lee SY, Lin M, Lee A, Park YI. Lanthanide-Doped Nanoparticles for Diagnostic Sensing. Nanomaterials. 2017; 7(12):411.

Chicago/Turabian Style

Lee, Song Y., Min Lin, Aeju Lee, and Yong I. Park 2017. "Lanthanide-Doped Nanoparticles for Diagnostic Sensing" Nanomaterials 7, no. 12: 411.

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