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Nanomaterials 2013, 3(2), 242-271;

Nanostructured Biomaterials and Their Applications

Princeton Institute for the Science and Technology of Materials, Princeton Imaging and Analysis Center, Princeton University, 120 Bowen Hall, Princeton, NJ 08544, USA
Author to whom correspondence should be addressed.
Received: 18 March 2013 / Revised: 23 April 2013 / Accepted: 24 April 2013 / Published: 10 May 2013
(This article belongs to the Special Issue Trends of Nanomaterials in Life Sciences)
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Some of the most important advances in the life sciences have come from transitioning to thinking of materials and their properties on the nanoscale rather than the macro or even microscale. Improvements in imaging technology have allowed us to see nanofeatures that directly impact chemical and mechanical properties of natural and man-made materials. Now that these can be imaged and quantified, substantial advances have been made in the fields of biomimetics, tissue engineering, and drug delivery. For the first time, scientists can determine the importance of nanograins and nanoasperities in nacre, direct the nucleation of apatite and the growth of cells on nanostructured scaffolds, and pass drugs tethered to nanoparticles through the blood-brain barrier. This review examines some of the most interesting materials whose nanostructure and hierarchical organization have been shown to correlate directly with favorable properties and their resulting applications. View Full-Text
Keywords: nacre; nanoparticles; hydroxyapatite; drug delivery; nanostructured scaffolds; biomimetics nacre; nanoparticles; hydroxyapatite; drug delivery; nanostructured scaffolds; biomimetics

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Parratt, K.; Yao, N. Nanostructured Biomaterials and Their Applications. Nanomaterials 2013, 3, 242-271.

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