Next Article in Journal
Data Shepherding in Nanotechnology. The Exposure Field Campaign Template
Previous Article in Journal
Highly Efficient and Wide Range Humidity Response of Biocompatible Egg White Thin Film
Article

Magnetic and Highly Luminescent Heterostructures of Gd3+/ZnO Conjugated to GCIS/ZnS Quantum Dots for Multimodal Imaging

1
Department of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Highway Araraquara-Jaú, Araraquara 14800-903, SP, Brazil
2
MINT, INSERM, CNRS, SFR-ICAT, UNIV Angers, 49000 Angers, France
3
PRISM, SFR-ICAT, UNIV Angers, 49000 Angers, France
4
Laboratório de Materiais Luminescentes Micro e Nanoestruturados—Mater Lumen, Departamento de Química, FFCLRP, Universidade de São Paulo (USP), Ribeirão Preto 14040-901, SP, Brazil
*
Author to whom correspondence should be addressed.
Academic Editor: Julian Maria Gonzalez Estevez
Nanomaterials 2021, 11(7), 1817; https://doi.org/10.3390/nano11071817
Received: 11 June 2021 / Revised: 5 July 2021 / Accepted: 6 July 2021 / Published: 13 July 2021
(This article belongs to the Section Nanocomposite Materials)
In recent years, the use of quantum dots (Qdots) to obtain biological images has attracted attention due to their excellent luminescent properties and the possibility of their association with contrast agents for magnetic resonance imaging (MRI). In this study, Gd3+/ZnO (ZnOGd) were conjugated with Qdots composed of a gadolinium-copper-indium-sulphur core covered with a ZnS shell (GCIS/ZnS Qdots). This conjugation is an innovation that has not yet been described in the literature, and which aims to improve Qdot photoluminescent properties. Structural and morphological Qdots features were obtained by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermogravimetric analyses (TGA). The photoluminescent properties were examined by emission (PL) and excitation (PLE) spectra. A new ZnOGd and GCIS/ZnS (ZnOGd-GCIS/ZnS) nanomaterial was synthesized with tunable optical properties depending on the ratio between the two native Qdots. A hydrophilic or lipophilic coating, using 3-glycidyloxypropyltrimethoxysilane (GPTMS) or hexadecyltrimethoxysilane (HTMS) on the surface of ZnOGd-GCIS/ZnS Qdots, was carried out before assessing their efficiency as magnetic resonance contrast agents. ZnOGd-GCIS/ZnS had excellent luminescence and MRI properties. The new Qdots developed ZnOGd-GCIS/ZnS, mostly constituted of ZnOGd (75%), which had less cytotoxicity when compared to ZnOGd, as well as greater cellular uptake. View Full-Text
Keywords: quantum dots; magnetic resonance imaging; luminescent properties; cytotoxicity quantum dots; magnetic resonance imaging; luminescent properties; cytotoxicity
Show Figures

Graphical abstract

MDPI and ACS Style

Lallo da Silva, B.; Lemaire, L.; Benoit, J.-P.; Borges, F.H.; Gonçalves, R.R.; Amantino, C.F.; Primo, F.L.; Chiavacci, L.A. Magnetic and Highly Luminescent Heterostructures of Gd3+/ZnO Conjugated to GCIS/ZnS Quantum Dots for Multimodal Imaging. Nanomaterials 2021, 11, 1817. https://doi.org/10.3390/nano11071817

AMA Style

Lallo da Silva B, Lemaire L, Benoit J-P, Borges FH, Gonçalves RR, Amantino CF, Primo FL, Chiavacci LA. Magnetic and Highly Luminescent Heterostructures of Gd3+/ZnO Conjugated to GCIS/ZnS Quantum Dots for Multimodal Imaging. Nanomaterials. 2021; 11(7):1817. https://doi.org/10.3390/nano11071817

Chicago/Turabian Style

Lallo da Silva, Bruna, Laurent Lemaire, Jean-Pierre Benoit, Fernanda H. Borges, Rogéria R. Gonçalves, Camila F. Amantino, Fernando L. Primo, and Leila A. Chiavacci 2021. "Magnetic and Highly Luminescent Heterostructures of Gd3+/ZnO Conjugated to GCIS/ZnS Quantum Dots for Multimodal Imaging" Nanomaterials 11, no. 7: 1817. https://doi.org/10.3390/nano11071817

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop