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Open AccessArticle

Acoustic Multi-Detection of Gliadin Using QCM Crystals Patterned with Controlled Sectors of TEM Grid and Annealed Nanoislands on Gold Electrode

1
Laboratoire Lumière, Nanomatériaux et Nanotechnologies – L2n, Université de Technologie de Troyes, CNRS ERL 7004, 12 rue Marie Curie, CS 42060, 10004 Troyes CEDEX, France
2
Dipartimento di Scienze Agroalimentari, Ambientali e Animali (DI4A), Università degli Studi di Udine, Via Sondrio 2/A, 33,100 Udine, Italy
*
Author to whom correspondence should be addressed.
Nanomaterials 2020, 10(4), 790; https://doi.org/10.3390/nano10040790
Received: 29 February 2020 / Revised: 16 April 2020 / Accepted: 17 April 2020 / Published: 20 April 2020
(This article belongs to the Section Synthesis, Interfaces and Nanostructures)
Celiac diseases are a group of gluten ingestion-correlated pathologies that are widespread and, in some cases, very dangerous for human health. The only effective treatment is the elimination of gluten from the diet throughout life. Nowadays, the food industries are very interested in cheap, easy-to-handle methods for detecting gluten in food, in order to provide their consumers with safe and high-quality food. Here, for the first time, the manufacture of controlled micropatterns of annealed gold nanoislands (AuNIs) on a single QCM crystal (QCM-color) and their biofunctionalization for the specific detection of traces of gliadin is reported. In addition, the modified quartz crystal with a TEM grid and 30 nm Au (Q-TEM grid crystal) is proposed as an acoustic sensitive biosensing platform for the rapid screening of the gliadin content in real food products. View Full-Text
Keywords: patterning nanoislands; annealed gold films; annealed quartz; Q-TEM and QCM-color crystals; multi-sensing platforms; gliadin patterning nanoislands; annealed gold films; annealed quartz; Q-TEM and QCM-color crystals; multi-sensing platforms; gliadin
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Casari Bariani, G.; Zhou, L.; Poggesi, S.; Mittapalli, R.; Manzano, M.; Ionescu, R.E. Acoustic Multi-Detection of Gliadin Using QCM Crystals Patterned with Controlled Sectors of TEM Grid and Annealed Nanoislands on Gold Electrode. Nanomaterials 2020, 10, 790.

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