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Article

Metadata Stewardship in Nanosafety Research: Community-Driven Organisation of Metadata Schemas to Support FAIR Nanoscience Data

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School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK
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Novamechanics Ltd., 1065 Nicosia, Cyprus
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Pennsylvania Bio Nano Systems, Doylestown, PA 18901, USA
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Edelweiss Connect, CH-4057 Basel, Switzerland
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Department of Biosciences, Paris Lodron University of Salzburg, 5020 Salzburg, Austria
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U.S. Army Public Health Center (APHC), Aberdeen Proving Ground—South, Aberdeen, MD 21010, USA
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School of Chemical Engineering, National Technical University of Athens, 157 80 Athens, Greece
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Mark D Hoover LLC, Morgantown, WV 26505, USA
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Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
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R&R Data Services, Gaithersburg, MD 20877, USA
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CODATA-VAMAS Working Group on Nanomaterials, 75016 Paris, France
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Biomax Informatics AG, 82152 Planegg, Germany
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Authors to whom correspondence should be addressed.
Nanomaterials 2020, 10(10), 2033; https://doi.org/10.3390/nano10102033
Received: 23 September 2020 / Revised: 8 October 2020 / Accepted: 11 October 2020 / Published: 15 October 2020
(This article belongs to the Special Issue From Nanoinformatics to Nanomaterials Risk Assessment and Governance)
The emergence of nanoinformatics as a key component of nanotechnology and nanosafety assessment for the prediction of engineered nanomaterials (NMs) properties, interactions, and hazards, and for grouping and read-across to reduce reliance on animal testing, has put the spotlight firmly on the need for access to high-quality, curated datasets. To date, the focus has been around what constitutes data quality and completeness, on the development of minimum reporting standards, and on the FAIR (findable, accessible, interoperable, and reusable) data principles. However, moving from the theoretical realm to practical implementation requires human intervention, which will be facilitated by the definition of clear roles and responsibilities across the complete data lifecycle and a deeper appreciation of what metadata is, and how to capture and index it. Here, we demonstrate, using specific worked case studies, how to organise the nano-community efforts to define metadata schemas, by organising the data management cycle as a joint effort of all players (data creators, analysts, curators, managers, and customers) supervised by the newly defined role of data shepherd. We propose that once researchers understand their tasks and responsibilities, they will naturally apply the available tools. Two case studies are presented (modelling of particle agglomeration for dose metrics, and consensus for NM dissolution), along with a survey of the currently implemented metadata schema in existing nanosafety databases. We conclude by offering recommendations on the steps forward and the needed workflows for metadata capture to ensure FAIR nanosafety data. View Full-Text
Keywords: nanosafety; (meta)data; data curation; data management roles; data shepherd; FAIR scientific principles nanosafety; (meta)data; data curation; data management roles; data shepherd; FAIR scientific principles
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MDPI and ACS Style

Papadiamantis, A.G.; Klaessig, F.C.; Exner, T.E.; Hofer, S.; Hofstaetter, N.; Himly, M.; Williams, M.A.; Doganis, P.; Hoover, M.D.; Afantitis, A.; Melagraki, G.; Nolan, T.S.; Rumble, J.; Maier, D.; Lynch, I. Metadata Stewardship in Nanosafety Research: Community-Driven Organisation of Metadata Schemas to Support FAIR Nanoscience Data. Nanomaterials 2020, 10, 2033. https://doi.org/10.3390/nano10102033

AMA Style

Papadiamantis AG, Klaessig FC, Exner TE, Hofer S, Hofstaetter N, Himly M, Williams MA, Doganis P, Hoover MD, Afantitis A, Melagraki G, Nolan TS, Rumble J, Maier D, Lynch I. Metadata Stewardship in Nanosafety Research: Community-Driven Organisation of Metadata Schemas to Support FAIR Nanoscience Data. Nanomaterials. 2020; 10(10):2033. https://doi.org/10.3390/nano10102033

Chicago/Turabian Style

Papadiamantis, Anastasios G., Frederick C. Klaessig, Thomas E. Exner, Sabine Hofer, Norbert Hofstaetter, Martin Himly, Marc A. Williams, Philip Doganis, Mark D. Hoover, Antreas Afantitis, Georgia Melagraki, Tracy S. Nolan, John Rumble, Dieter Maier, and Iseult Lynch. 2020. "Metadata Stewardship in Nanosafety Research: Community-Driven Organisation of Metadata Schemas to Support FAIR Nanoscience Data" Nanomaterials 10, no. 10: 2033. https://doi.org/10.3390/nano10102033

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