Updates in Stroke Treatment, Diagnostic Methods and Predictors of Outcome
1. Introduction
1.1. Considerations and Improvements in Acute Stroke Reperfusion Therapies
1.2. Emerging Applications of Neurosonology in Stroke
1.3. Novel Predictors of Stroke Outcome
2. Conclusions
Funding
Conflicts of Interest
Disclosures
References
- Baek, J.-H.; Kim, B.M.; Kim, J.W.; Kim, D.J.; Heo, J.H.; Nam, H.S.; Kim, Y.D. Utility of Leptomeningeal Collaterals in Predicting Intracranial Atherosclerosis-Related Large Vessel Occlusion in Endovascular Treatment. J. Clin. Med. 2020, 9, 2784. [Google Scholar] [CrossRef]
- Katsanos, A.H.; Hart, R.G. New horizons in pharmacologic therapy for secondary stroke prevention. JAMA Neurol. 2020. [Google Scholar] [CrossRef]
- Rabinstein, A.A. Update on treatment of acute ischemic stroke. Continuum Minneap Minn 2020, 26, 268–286. [Google Scholar] [CrossRef]
- Tsivgoulis, G.; Safouris, A.; Katsanos, A.H.; Arthur, A.S.; Alexandrov, A.V. Mechanical thrombectomy for emergent large vessel occlusion: A critical appraisal of recent randomized controlled clinical trials. Brain Behav. 2016, 6, e00418. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Nogueira, R.G.; Jadhav, A.P.; Haussen, D.C.; Bonafe, A.; Budzik, R.F.; Bhuva, P.; Yavagal, D.R.; Ribo, M.; Cognard, C.; Hanel, R.A.; et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N. Engl. J. Med. 2018, 378, 11–21. [Google Scholar] [CrossRef]
- Albers, G.W.; Marks, M.P.; Kemp, S.; Christensen, S.; Tsai, J.P.; Ortega-Gutierrez, S.; McTaggart, R.A.; Torbey, M.T.; Kim-Tenser, M.; Leslie-Mazwi, T.; et al. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N. Engl. J. Med. 2018, 378, 708–718. [Google Scholar] [CrossRef] [PubMed]
- Tsivgoulis, G.; Katsanos, A.H.; Malhotra, K.; Sarraj, A.; Barreto, A.D.; Köhrmann, M.; Krogias, C.; Ahmed, N.; Caso, V.; Schellinger, P.D.; et al. Thrombolysis for acute ischemic stroke in the unwitnessed or extended therapeutic time window. Neurology 2020, 94, e1241–e1248. [Google Scholar] [CrossRef]
- Khatri, P.; Kleindorfer, D.O.; Devlin, T.; Sawyer, R.N., Jr.; Starr, M.; Mejilla, J.; Broderick, J.; Chatterjee, A.; Jauch, E.C.; Levine, S.R.; et al. Effect of alteplase vs aspirin on functional outcome for patients with acute ischemic stroke and minor nondisabling neurologic deficits: The PRISMS randomized clinical trial. JAMA 2018, 320, 156–166. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Merlino, G.; Smeralda, C.; Lorenzut, S.; Gigli, G.L.; Surcinelli, A.; Valente, M. To treat or not to treat: Importance of functional dependence in deciding intravenous thrombolysis of “mild stroke” patients. J. Clin. Med. 2020, 9, 768. [Google Scholar] [CrossRef] [Green Version]
- Tsivgoulis, G.; Katsanos, A.H.; Alexandrov, A.V. Reperfusion therapies of acute ischemic stroke: Potentials and failures. Front. Neurol. 2014, 5, 215. [Google Scholar] [CrossRef]
- Kim, Y.D.; Heo, J.H.; Yoo, J.; Park, H.; Kim, B.M.; Bang, O.Y.; Kim, H.C.; Han, E.; Kim, D.J.; Heo, J.; et al. Improving the clinical outcome in stroke patients receiving thrombolytic or endovascular treatment in korea: From the SECRET study. J. Clin. Med. 2020, 9, 717. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Bourcier, R.; Goyal, M.; Liebeskind, D.S.; Muir, K.W.; Desal, H.; Siddiqui, A.H.; Dippel, D.W.J.; Majoie, C.B.; van Zwam, W.H.; Jovin, T.G.; et al. Association of time from stroke onset to groin puncture with quality of reperfusion after mechanical thrombectomy: A meta-analysis of individual patient data from 7 randomized clinical trials. JAMA Neurol. 2019, 76, 405–411. [Google Scholar] [CrossRef] [PubMed]
- Psychogios, M.N.; Behme, D.; Schregel, K.; Tsogkas, I.; Maier, I.L.; Leyhe, J.R.; Zapf, A.; Tran, J.; Bähr, M.; Liman, J.; et al. One-stop management of acute stroke patients: Minimizing door-to-reperfusion times. Stroke 2017, 48, 3152–3155. [Google Scholar] [CrossRef] [PubMed]
- Wiśniewski, A.; Boinska, J.; Ziołkowska, K.; Lemanowicz, A.; Filipska, K.; Serafin, Z.; Ślusarz, R.; Rość, D.; Kozera, G. Endothelial progenitor cells as a marker of vascular damage but not a predictor in acute microangiopathy-associated stroke. J. Clin. Med. 2020, 9, 2248. [Google Scholar] [CrossRef]
- Matias-Guiu, J.A.; Serna-Candel, C.; Matias-Guiu, J. Stroke etiology determines effectiveness of retrievable stents. J. Neurointerv. Surg. 2014, 6, e11. [Google Scholar] [CrossRef]
- Psychogios, M.N.; Maier, I.L.; Tsogkas, I.; Hesse, A.C.; Brehm, A.; Behme, D.; Schnieder, M.; Schregel, K.; Papageorgiou, I.; Liebeskind, D.S.; et al. One-stop management of 230 consecutive acute stroke patients: report of procedural times and clinical outcome. J. Clin. Med. 2019, 8, 2185. [Google Scholar] [CrossRef] [Green Version]
- Sposato, L.A.; Cipriano, L.E.; Saposnik, G.; Ruνz Vargas, E.; Riccio, P.M.; Hachinski, V. Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: A systematic review and meta-analysis. Lancet Neurol. 2015, 14, 377–387. [Google Scholar] [CrossRef]
- Kernan, W.N.; Ovbiagele, B.; Black, H.R.; Bravata, D.M.; Chimowitz, M.I.; Ezekowitz, M.D.; Fang, M.C.; Fisher, M.; Furie, K.L.; Heck, D.V.; et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: A guideline for healthcare professionals from the american heart association/american stroke association. Stroke 2014, 45, 2160–2236. [Google Scholar] [CrossRef]
- Liantinioti, C.; Palaiodimou, L.; Tympas, K.; Parissis, J.; Theodorou, A.; Ikonomidis, I.; Chondrogianni, M.; Zompola, C.; Triantafyllou, S.; Roussopoulou, A.; et al. Potential utility of neurosonology in paroxysmal atrial fibrillation detection in patients with cryptogenic stroke. J. Clin. Med. 2019, 8, 2002. [Google Scholar] [CrossRef] [Green Version]
- Triantafyllou, S.; Katsanos, A.H.; Dilaveris, P.; Giannopoulos, G.; Kossyvakis, C.; Adreanides, E.; Liantinioti, C.; Tympas, K.; Zompola, C.; Theodorou, A.; et al. Implantable cardiac monitoring in the secondary prevention of cryptogenic stroke. Ann. Neurol. 2020. [Google Scholar] [CrossRef]
- Park, H.; Han, M.; Kim, Y.D.; Yoo, J.; Lee, H.S.; Choi, J.K.; Heo, J.H.; Nam, H.S. Impact of the total number of carotid plaques on the outcome of ischemic stroke patients with atrial fibrillation. J. Clin. Med. 2019, 8, 1897. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Eyding, J.; Fung, C.; Niesen, W.D.; Krogias, C. Twenty years of cerebral ultrasound perfusion imaging—Is the best yet to come? J. Clin. Med. 2020, 9, 816. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Jampathong, N.; Laopaiboon, M.; Rattanakanokchai, S.; Pattanittum, P. Prognostic models for complete recovery in ischemic stroke: A systematic review and meta-analysis. BMC Neurol. 2018, 18, 26. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Min, Y.S.; Park, J.W.; Park, E.; Kim, A.-R.; Cha, H.; Gwak, D.-W.; Jung, S.-H.; Chang, Y.; Jung, T.-D. Interhemispheric functional connectivity in the primary motor cortex assessed by resting-state functional magnetic resonance imaging aids long-term recovery prediction among subacute stroke patients with severe hand weakness. J. Clin. Med. 2020, 9, 975. [Google Scholar] [CrossRef] [Green Version]
- Tsivgoulis, G.; Bogiatzi, C.; Heliopoulos, I.; Vadikolias, K.; Boutati, E.; Tsakaldimi, S.; Al-Attas, O.S.; Charalampidis, P.; Piperidou, C.; Maltezos, E.; et al. Low ankle-brachial index predicts early risk of recurrent stroke in patients with acute cerebral ischemia. Atherosclerosis 2012, 220, 407–412. [Google Scholar] [CrossRef]
- Han, M.; Kim, Y.D.; Choi, J.K.; Choi, J.; Ha, J.; Park, E.; Kim, J.; Song, T.-J.; Heo, J.H.; Nam, H.S. Predicting stroke outcomes using ankle-brachial index and inter-ankle blood pressure difference. J. Clin. Med. 2020, 9, 1125. [Google Scholar] [CrossRef] [Green Version]
- Kim, C.; Lee, S.H.; Lim, J.S.; Oh, M.S.; Yu, K.-H.; Kim, Y.; Lee, J.-H.; Jang, M.U.; Jung, S.; Lee, B.-C. Timing of transfusion, not hemoglobin variability, is associated with 3-month outcomes in acute ischemic stroke. J. Clin. Med. 2020, 9, 1566. [Google Scholar] [CrossRef]
- Fiolaki, A.; Katsanos, A.H.; Kyritsis, A.P.; Papadaki, S.; Kosmidou, M.; Moschonas, I.C.; Tselepis, A.D.; Giannopoulos, S. High on treatment platelet reactivity to aspirin and clopidogrel in ischemic stroke: A systematic review and meta-analysis. J. Neurol. Sci. 2017, 376, 112–116. [Google Scholar] [CrossRef]
- Wiśniewski, A.; Sikora, J.; Sławińska, A.; Filipska, K.; Karczmarska-Wódzka, A.; Serafin, Z.; Kozera, G. High on-treatment platelet reactivity affects the extent of ischemic lesions in stroke patients due to large-vessel disease. J. Clin. Med. 2020, 9, 251. [Google Scholar] [CrossRef] [Green Version]
- Wiśniewski, A.; Filipska, K.; Sikora, J.; Ślusarz, R.; Kozera, G. The Prognostic Value of High Platelet Reactivity in Ischemic Stroke Depends on the Etiology: A Pilot Study. J. Clin. Med. 2020, 9, 859. [Google Scholar] [CrossRef] [Green Version]
© 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Katsanos, A.H. Updates in Stroke Treatment, Diagnostic Methods and Predictors of Outcome. J. Clin. Med. 2020, 9, 2789. https://doi.org/10.3390/jcm9092789
Katsanos AH. Updates in Stroke Treatment, Diagnostic Methods and Predictors of Outcome. Journal of Clinical Medicine. 2020; 9(9):2789. https://doi.org/10.3390/jcm9092789
Chicago/Turabian StyleKatsanos, Aristeidis H. 2020. "Updates in Stroke Treatment, Diagnostic Methods and Predictors of Outcome" Journal of Clinical Medicine 9, no. 9: 2789. https://doi.org/10.3390/jcm9092789